Compare Jardiance vs. Onglyza
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood sugar.
Jardiance (empagliflozin) lowers blood sugar for people with diabetes, but can increase the chance of a yeast infection.
Lowers blood sugar.
Onglyza (saxagliptin) can cause heart failure unlike other medicines that work just like it.
- Lowers A1c (average blood sugar over time) levels up to 1%.
- Can prevent death from heart attack, stroke, or heart failure if you have pre-existing heart disease.
- Can be easily taken orally as a pill.
- Can cause weight loss.
- Not likely to cause hypoglycemia or very low blood sugar.
- DRUG-NAME is an oral blood sugar lowering medicine. It's a good option if you don't like injections.
- Does not cause weight gain.
- May be a good option for those with bad liver function.
- Does not cause hypoglycemia (low blood sugar) when taken by itself.
- More expensive since it's available as brand name only.
- Can cause dehydration.
- Typically not first-choice treatment for diabetes.
- Only lowers A1C (average blood sugar over time) by ~0.5%.
- Risk for heart failure has not been seen in other medicines that work just like it.
- May be more expensive than other anti-diabetic medicines.
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9possible side effects
- Low blood sugar40%
- Urinary tract infection9%
- Yeast infection in women5%
- Elevated cholesterol levels4%
- Head cold3%
- Increased urination3%
- Yeast infection in men3%
- Joint pain2%
The Onglyza (saxagliptin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Low blood pressure
- Over age 65
- Kidney disease
- Taking blood pressure medications
- Worsening kidney function
- Poor baseline kidney function
- Congestive heart failure
- Too much acid in the blood
- Type 1 diabetes
- Extended fasting
- Yeast infections and urinary tract infections
- inflammation of the pancreas
- Elevated triglycerides
- History of pancreatitis
- Heart failure
- History of heart failure
- Bad kidney function
- Low blood sugar (hypoglycemia)
- Unexpected changes in diet
- Changes in amount of exercise
- Taking other anti-diabetic medications
- Severe allergic reactions
- Severe joint pain
- Fluid-filled blisters on the skin (bullous pemphigoid)