Compare Kaletra vs. Aptivus

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Kaletra (lopinavir / ritonavir)

Prescription only

Aptivus (tipranavir)

Prescription only
Treats HIV infection.

Kaletra (lopinavir / ritonavir) is not commonly used to treat HIV because of its side effects and the number of pills you have to take daily.

Treats HIV infection.

Aptivus (tipranavir) is not the first-choice treatment for HIV because it can cause more side effects and drug interactions than similar alternatives.

Upsides
  • Kaletra (lopinavir / ritonavir) can be taken once or twice daily.
  • Tablets can be taken with or without food.
  • An oral solution is available if tablets are hard to swallow.
  • Aptivus (tipranavir) comes in liquid form if you have trouble swallowing pills.
  • Children as young as 2 years old can use Aptivus (tipranavir) safely and effectively.
Downsides
  • Has more side-effects compared to newer medicines that work like it.
  • You may have to take up to 4 tablets to meet your required daily dose.
  • Interacts with many other medicines and supplements.
  • Can increase your risk for a heart attack.
  • Aptivus (tipranavir) can cause high cholesterol and high blood sugars.
  • Aptivus (tipranavir) isn't a good option if you have a sulfa allergy.
  • Use barrier contraceptives, like condoms, when taking Aptivus (tipranavir) because it can make birth control pills less effective.
  • Aptivus (tipranavir) should always be taken with Norvir (ritonavir) to be effective.
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Used for
Dosage forms
  • Pill
  • Liquid
  • Pill
  • Liquid
Price
Lowest price
$128.10
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Lowest price
$1848.95
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Reviews
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Side effects
35possible side effects
  • Diarrhea
    20%
  • Upper respiratory tract infection
    14%
  • Nausea
    10%
  • Fatigue and weakness
    8%
  • Lower respiratory tract infection
    8%
  • Vomiting
    7%
  • High cholesterol
    7%
  • Bone, joint and back pain
    7%
  • Abdominal pain
    6%
  • High fats
    6%
  • Headaches including migraines
    6%
  • Hepatitis and changes in liver function tests
    4%
  • Insomnia
    4%
  • Anxiety
    4%
  • Skin rashes
    4%
  • Inflammation in the stomach or intestines
    3%
  • Skin allergies, hives and facial swelling
    3%
  • Skin infections
    3%
  • Anemia
    2%
  • Decreased white blood cells
    2%
  • Indigestion
    2%
  • Pancreatitis
    2%
  • Acid reflux
    2%
  • Hemorrhoids
    2%
  • Weight loss
    2%
  • Loss of appetite
    2%
  • Muscle pain
    2%
  • Nerve damage
    2%
  • Dizziness
    2%
  • Erectile dysfunction
    2%
  • Menstrual bleeding problems
    2%
  • Changes in fat distribution
    2%
  • Eczema
    2%
  • Night sweats
    2%
  • High blood pressure
    2%
See more detailed side effects
20possible side effects
  • Diarrhea
    15%
  • Nausea
    9%
  • Fever
    8%
  • Vomiting
    6%
  • Fatigue
    6%
  • Headache
    5%
  • Abdominal pain
    4%
  • High triglycerides
    4%
  • Low red blood cells
    3%
  • Decreased weight
    3%
  • High cholesterol
    3%
  • Rash
    3%
  • Low white blood cells
    2%
  • Upper abdominal pain
    2%
  • Elevated liver function tests
    2%
  • Dehydration
    2%
  • Muscle pain
    2%
  • Nerve damage
    2%
  • Insomnia
    2%
  • Shortness of breath
    2%
See more detailed side effects
Risks and risk factors
  • Liver damage
    • History of liver damage
    • Hepatitis B or C
  • Heart (atrioventricular) block
    • Use with other QT or PR prolonging drugs
    • History of heart disease
    • Low potassium levels
  • Immune recovery syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Fat redistribution
  • New or worsening diabetes
    • Use of protease inhibitors
    • Diabetes
  • Pancreatitis
    • Advanced HIV disease
    • History of pancreatitis
See more detailed risks and warnings
  • Bleeding in the brain
  • Immune reconstitution syndrome
    • HIV
    • Exposure to other infections
    • Start of a new HIV medication
    • Change in HIV therapy
  • Liver damage
    • History of liver damage
    • Hepatitis B or C
  • Rash
  • Sulfa allergy
  • Fat redistribution
    • HIV treatment
See more detailed risks and warnings
Learn more about Kaletra (lopinavir / ritonavir)
Learn more about Aptivus (tipranavir)