Compare Kapvay vs. Dexedrine

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Kapvay (clonidine)

Prescription only
Treats attention deficit hyperactivity disorder.

Kapvay (clonidine) is one of the few medicines for ADHD that isn't a stimulant and not addictive, but it can lower your blood pressure.

Treats attention deficit disorder.

Dexedrine (dextroamphetamine) is an effective medicine for treatment of ADHD, but often abused for recreational purposes.

4.3/ 5 average rating with 28 reviewsforDexedrine
  • Can be used alone or together with a stimulant-type medicine to treat ADHD.
  • Also treats blood pressure and some nervous system and psychiatric conditions.
  • Kapvay (clonidine) is available in generic.
  • Recommended as a first-choice treatment of ADHD.
  • Available as generic version.
  • For more flexible dosing schedule, Dexedrine (dextroamphetamine) is available in short and long formulations.
  • If you have difficulty swallowing pills, Dexedrine (dextroamphetamine) is available as a liquid.
  • Kapvay (clonidine) is not a first choice medicine to treat ADHD.
  • Kapvay (clonidine) can make you feel very dizzy or cause low blood pressure.
  • Stopping Kapvay (clonidine) suddenly can cause your blood pressure to jump and your heart to beat very fast.
  • It can take up to two weeks of taking Kapvay (clonidine) to notice any changes in behavior.
  • Kapvay (clonidine) has to be swallowed whole, which can be hard for some children to do.
  • Taking Dexedrine (dextroamphetamine) can decrease your appetite.
  • If taken late in the day, Dexedrine (dextroamphetamine) can cause insomnia.
  • People who take high doses of Dexedrine (dextroamphetamine) are more likely to have anxiety, restlessness, or irritability.
  • Requires a new prescription from your doctor every month.
  • Not a good option if you have a history of seizures.
  • Can be habit-forming so make sure you use it only as prescribed.
Used for
Dosage forms
  • Extended release
  • Pill
  • Extended release
  • Liquid
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28 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

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Side effects
12possible side effects
  • Sleepiness
  • Fatigue
  • Headache
  • Upper abdominal pain
  • Decreased appetite 
  • Dizziness
  • Insomnia
  • Aggression
  • Mood changes
  • Emotional disorders
  • Irritability
  • Stuffy nose
See more detailed side effects
The Dexedrine (dextroamphetamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Low blood pressure and low heart rate
  • Sleepiness
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • High blood pressure
    • Stopping Kapvay (clonidine) suddenly
See more detailed risks and warnings
  • Abuse and dependence
    • History of drug abuse
  • Serious or life-threatening heart problems
    • History of heart problems
  • Aggressive behavior and psychosis
    • History of psychotic episodes
    • History of bipolar disorder
  • Long-term growth suppression
    • Children
  • Seizures
    • History of seizures
  • Serotonin Syndrome (rare, life-threatening)
    • Using other medicines that increase serotonin levels in the brain
See more detailed risks and warnings