Compare Keflex vs. Cleocin
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats bacterial infections.
Keflex (cephalexin) is good for treating many bacterial infections, and is available as a generic.
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3.7/ 5 average rating with 686 reviewsforKeflex
Treats acne.
Cleocin (clindamycin) is proven to be effective at treating acne when combined with another acne medicine and is available in a variety of formulations.
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3.5/ 5 average rating with 115 reviewsforCleocin
Upsides
- Available in generic.
- Available in different forms: tablet, capsule, and suspension.
- Used to treat many types of bacterial infections.
- Can be taken with or without food.
- Generally few side effects compared with other antibiotics.
- Available in generic.
- Comes in different formulations (gel, solution, lotion, foam) to fit your preferences.
- Works well for the kind of acne that causes large, red, and swollen pimples.
Downsides
- Can cause diarrhea.
- You may need to take Keflex (cephalexin) 2 to 4 times a day, which can be hard to remember.
- If you're allergic to penicillins or other antibiotics, you might not be able to take this medicine.
- Foam formulation can cause headaches.
- You will likely have to use another acne medicine along with Cleocin (clindamycin) since it is not as effective by itself.
- Is only preferred for mild to moderate acne. If you have severe acne your doctor will most likely prescribe an oral medication.
- If you only have comedonal acne (small skin-colored bumps on the skin) without any red, swollen pimples, your doctor may give you an alternative medicine.
Used for
- Bone infection
- Urinary tract infection
- Ear infection
- Respiratory tract infection
- Skin infection
- Community-acquired pneumonia
- Prevention of endocarditis
- Prevention of infection in people with prosthetic joint implants undergoing dental procedure
- Prosthetic joint infection
- Surgical site infection
Dosage forms
- Pill
- Liquid
- Gel
- Foam
- Solution
- Lotion
Price
Lowest price
$9.05
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$124.00
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Reviews
686 reviews so far
64%
saidit'sworth it
48%
saiditworked well
14%
saidit'sa big hassle
Have you used Keflex (cephalexin)?
Leave a review115 reviews so far
57%
saidit'sworth it
43%
saiditworked well
19%
saidit'sa big hassle
Have you used Cleocin (clindamycin)?
Leave a reviewSide effects
The Keflex (cephalexin) FDA package insert doesn’t have numbers about how common side effects are.
9possible side effects
- Dryness23%
- Oiliness/Oily skin18%
- Redness16%
- Burning11%
- Burning/Itching11%
- Peeling11%
- Itching11%
- Burning where applied6%
- Headache3%
Risks and risk factors
- Diarrhea
- New infections while taking Keflex (cephalexin)
- Weakened immune system
- Not taking Keflex (cephalexin) correctly
- Allergic reaction
- History of penicillin or cephalosporin allergies
- Skin irritation
- Using other medicines or products that irritate the skin
- Eczema
- Extreme temperatures (hot or cold)
- Severe diarrhea and stomach cramps
- Using Cleocin (clindamycin) for a long time