Compare Ketoconazole vs. Cresemba

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Nizoral (Ketoconazole)

Prescription or OTC
Treats fungal infections.

Nizoral (Ketoconazole) is a medication used on your skin to treat fungal infections; however, it takes several weeks for full recovery, and the directions are specific to each type of medication.

Treats serious fungal infections.

Cresemba (isavuconazonium) is used to treat serious fungal infections as an alternative if you had problems with first choice medicines. However, it can be very expensive.

Upsides
  • Recommended as a first choice medication to treat skin infections caused by fungi, including cradle cap, seborrheic dermatitis, and tinea versicolor.
  • Nizoral (Ketoconazole) isn't taken orally, so it doesn't cause liver issues.
  • Can be used with other medications to help control redness and swelling.
  • The 1% shampoo is available over-the-counter in the drugstore.
  • Unlike some other antifungal medications, you don’t need regular blood tests while you're taking Cresemba (isavuconazonium).
  • Cresemba (isavuconazonium) has fewer and milder side effects than other medicines for fungal infections.
  • You only need to take Cresemba (isavuconazonium) once a day after the first two days.
  • If you have conditions related to a slow or abnormal heartbeat, Cresemba (isavuconazonium) may be a good choice for treatment of a serious fungal infection.
  • Available in both an injectable form and capsules you take by mouth.
Downsides
  • The foams (Extina and Ketodan) and gel (Xolegel) are only available as brand name and can be more expensive.
  • The 2.5% shampoo and creams are available only by prescription, but are generic.
  • The shampoo has to be left on for at least 5-10 minutes after lathering before you rinse it off.
  • It can take a few weeks for the infection to clear and a few months before the skin returns to its normal color.
  • The fungal infections can be confused for other skin infections, so if Nizoral (Ketoconazole) doesn't work, it could be caused by another skin problem.
  • Cresemba (isavuconazonium) needs to be taken twice daily.
  • Cresemba (isavuconazonium) may cause serious blood, muscle and liver problems.
  • Cresemba (isavuconazonium) is not recommended if you have kidney damage.
  • Cresemba (isavuconazonium) has a high incidence of side effects, including nausea, vomiting, loss of appetite, headache and malaise.
  • Cresemba (isavuconazonium) can negatively affect your cholesterol and blood sugar levels.
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Used for
Dosage forms
  • Pill
  • Cream, gel, or ointment
  • Foam
  • Shampoo
  • Pill
  • Injection
Price
Lowest price
$4864.52
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Reviews
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Side effects
1possible side effects
  • Any side effect
    5%
See more detailed side effects
25possible side effects
  • Nausea
    28%
  • Vomiting
    25%
  • Diarrhea
    24%
  • Low potassium
    19%
  • Abdominal pain
    17%
  • Headache
    17%
  • Changes in liver blood tests
    17%
  • Trouble breathing
    17%
  • Swelling in the arms and legs
    15%
  • Constipation
    14%
  • Insomnia
    11%
  • Fatigue
    11%
  • Kidney failure
    10%
  • Back pain
    10%
  • Chest pain
    9%
  • Decreased appetite
    9%
  • Confusion/delirium
    9%
  • Skin rash
    9%
  • Itching
    8%
  • Low blood pressure
    8%
  • Anxiety
    8%
  • Acute respiratory failure
    7%
  • Indigestion
    6%
  • Injection site reactions
    6%
  • Low magnesium
    5%
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Risks and risk factors
  • Severe allergic reactions
    • Asthma
See more detailed risks and warnings
  • Liver problems
  • Infusion problems
  • Severe allergic reactions
  • Risks to fetus
    • Pregnancy
  • Drug interactions
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