Compare Klonopin vs. Buspar

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Klonopin (clonazepam)

Prescription only

Buspar (buspirone)

Prescription only
Controls seizures and helps panic attacks.

Klonopin (clonazepam) can be used for immediate relief of panic attacks and seizures, but is not intended for long-term management.

3.8/ 5 average rating with 767 reviewsforKlonopin
Helps you relax.

Buspar (buspirone) relieves anxiety with less drowsiness and abuse potential than other anti-anxiety medicines, but it takes time to work and effects might wear off over time.

3.4/ 5 average rating with 67 reviewsforBuspar
Upsides
  • More people who took Klonopin (clonazepam) were free of panic attacks, compared to people who did not take Klonopin (clonazepam).
  • Klonopin (clonazepam) works quickly, within the hour.
  • Can be used together with antidepressants to manage panic disorder.
  • Klonopin (clonazepam) lasts longer and has less severe withdrawal symptoms compared to other similar medicines.
  • Doesn't cause as much physical dependence or withdrawal symptoms as other medications used for anxiety.
  • Available as a generic, which is cheaper.
  • Tablets can be split for easy dose changes.
  • Doesn't cause as much drowsiness as other medications for anxiety.
Downsides
  • Klonopin (clonazepam) can cause memory problems, drowsiness, dizziness, and confusion.
  • Klonopin (clonazepam) can be habit-forming, so is not typically used for long-term treatment.
  • May require higher doses of Klonopin (clonazepam) over time to establish the same seizure control.
  • Not for quick relief of anxiety symptoms since Buspar (buspirone) can take as long as 4 weeks to fully work.
  • Not as effective for short-term anxiety conditions or panic disorders.
  • Some people find that Buspar (buspirone) loses effectiveness over long periods of time.
  • Must take Buspar (buspirone) twice daily for full effect.
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Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Pill
Price
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Reviews
767 reviews so far
70%
saidit'sworth it
52%
saiditworked well
14%
saidit'sa big hassle

Have you used Klonopin (clonazepam)?

Leave a review
67 reviews so far
46%
saidit'sworth it
45%
saiditworked well
22%
saidit'sa big hassle

Have you used Buspar (buspirone)?

Leave a review
Side effects
4possible side effects
  • Drowsiness
    37%
  • Depression
    7%
  • Abnormal coordination
    6%
  • Loss of full control of bodily movements
    5%
See more detailed side effects
19possible side effects
  • Dizziness
    12%
  • Drowsiness
    10%
  • Nausea
    8%
  • Headache
    6%
  • Nervousness
    5%
  • Fatigue
    4%
  • Trouble sleeping
    3%
  • Lightheadedness
    3%
  • Dry mouth
    3%
  • Worse concentration
    2%
  • Excitement
    2%
  • Anger/hostility
    2%
  • Confusion
    2%
  • Depression
    2%
  • Blurred vision
    2%
  • Upset stomach
    2%
  • Diarrhea
    2%
  • Numbness
    2%
  • Weakness
    2%
See more detailed side effects
Risks and risk factors
  • Sedation, respiratory depression, coma and death
    • Taking with opioids
    • Drinking alcohol
  • Dependence and withdrawal
    • Taking high dosage
    • Taking long-term
    • History of drug abuse
  • Driving impairment
    • Drinking alcohol
    • Taking other medicines that make you less alert
  • Suicidal behavior and ideation
See more detailed risks and warnings
  • Higher blood pressure
    • Taking Buspar (buspirone) with MAOIs
    • Taking Buspar (buspirone) within 14 days after stopping a MAOIs
  • Serotonin syndrome
    • Taking other medicines that affect serotonin levels
  • Withdrawal symptoms from other anti-anxiety medicines
    • Stopping benzodiazepines suddenly
See more detailed risks and warnings