Compare Klonopin vs. Lunesta

Head-to-head comparisons of medication uses, side effects, ratings, and more.


Klonopin (clonazepam)

Prescription only

Lunesta (Eszopiclone)

Prescription only
Controls seizures and helps panic attacks.

Klonopin (clonazepam) can be used for immediate relief of panic attacks and seizures, but is not intended for long-term management.

3.8/ 5 average rating with 767 reviewsforKlonopin
Helps you sleep.

Lunesta (Eszopiclone) is good for falling asleep and staying asleep. Not as habit-forming as some sleep medicines, but more likely to cause withdrawal symptoms if you stop suddenly.

3.3/ 5 average rating with 592 reviewsforLunesta
  • More people who took Klonopin (clonazepam) were free of panic attacks, compared to people who did not take Klonopin (clonazepam).
  • Klonopin (clonazepam) works quickly, within the hour.
  • Can be used together with antidepressants to manage panic disorder.
  • Klonopin (clonazepam) lasts longer and has less severe withdrawal symptoms compared to other similar medicines.
  • Effective at helping people fall asleep faster and sleep longer.
  • Not as habit-forming, so you can use it for longer than most other sleep medicines.
  • Klonopin (clonazepam) can cause memory problems, drowsiness, dizziness, and confusion.
  • Klonopin (clonazepam) can be habit-forming, so is not typically used for long-term treatment.
  • May require higher doses of Klonopin (clonazepam) over time to establish the same seizure control.
  • More likely to cause withdrawal symptoms if you stop taking it suddenly.
  • Might not be safe if you have a history of drug or alcohol abuse, depression, lung disease, or a condition that affects metabolism.
  • It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behavior so that you can sleep better naturally.
Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Pill
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767 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

Have you used Klonopin (clonazepam)?

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592 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

Have you used Lunesta (Eszopiclone)?

Leave a review
Side effects
4possible side effects
  • Drowsiness
  • Depression
  • Abnormal coordination
  • Loss of full control of bodily movements
See more detailed side effects
10possible side effects
  • Headache
  • Unpleasant Taste
  • Dyspepsia
  • Pain
  • Diarrhea
  • Pruritus
  • Dry Mouth
  • Abnormal Dreams
  • Neuralgia
  • Urinary Tract Infection
See more detailed side effects
Risks and risk factors
  • Sedation, respiratory depression, coma and death
    • Taking with opioids
    • Drinking alcohol
  • Dependence and withdrawal
    • Taking high dosage
    • Taking long-term
    • History of drug abuse
  • Driving impairment
    • Drinking alcohol
    • Taking other medicines that make you less alert
  • Suicidal behavior and ideation
See more detailed risks and warnings
  • Dependence and withdrawal
    • Continuous use for 2 weeks or more
  • Driving impairment
    • Alcohol
    • Taking other medicines that make you less alert
    • Less than 7 hours of sleep.
  • Abnormal thoughts
    • Undiagnosed psychiatric conditions
  • Sleep driving
    • Taking with alcohol or drugs that acts in the brain
  • Serious allergic reactions
  • Risk of falls and injury
    • Elderly
    • Higher dose
    • Liver problems
    • Taking Lunesta (Eszopiclone) with other nervous system depressants
    • Long-term use
  • Risk to fetus
    • Women of childbearing age
    • Breast-feeding
See more detailed risks and warnings