Compare Klonopin vs. Unisom

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Klonopin (clonazepam)

Prescription only

Unisom Sleeptabs (Doxylamine)

Prescription or OTC
Controls seizures and helps panic attacks.

Klonopin (clonazepam) can be used for immediate relief of panic attacks and seizures, but is not intended for long-term management.

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3.8/ 5 average rating with 767 reviewsforKlonopin
Treats allergy symptoms and helps you sleep.

Unisom Sleeptabs (Doxylamine) can help you get a good night's sleep, but you can have a hard time waking up if you don't give yourself enough time to sleep.

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3.3/ 5 average rating with 585 reviewsforUnisom
Upsides
  • More people who took Klonopin (clonazepam) were free of panic attacks, compared to people who did not take Klonopin (clonazepam).
  • Klonopin (clonazepam) works quickly, within the hour.
  • Can be used together with antidepressants to manage panic disorder.
  • Klonopin (clonazepam) lasts longer and has less severe withdrawal symptoms compared to other similar medicines.
  • Works well to help you fall asleep and doesn't make you feel groggy the next morning.
  • Has fewer side effects than prescription sleep aid medications.
  • Available over the counter without a prescription.
  • Not habit-forming like other sleep aids can be.
Downsides
  • Klonopin (clonazepam) can cause memory problems, drowsiness, dizziness, and confusion.
  • Klonopin (clonazepam) can be habit-forming, so is not typically used for long-term treatment.
  • May require higher doses of Klonopin (clonazepam) over time to establish the same seizure control.
  • Shouldn't be used unless you have a full night to sleep.
  • You shouldn't drive after taking Unisom Sleeptabs (Doxylamine) until you know how it affects you.
  • Drinking alcohol while taking Unisom Sleeptabs (Doxylamine) isn't recommended.
  • It can increase the risk of falls, so elderly people shouldn't use Unisom Sleeptabs (Doxylamine).
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Used for
Dosage forms
  • Pill
  • Dissolving tablet
  • Pill
  • Chewable tablet
  • Liquid
Price
Lowest price
$5.56
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Lowest price
$6.47
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Reviews
767 reviews so far
70%
saidit'sworth it
52%
saiditworked well
14%
saidit'sa big hassle

Have you used Klonopin (clonazepam)?

Leave a review
585 reviews so far
58%
saidit'sworth it
32%
saiditworked well
11%
saidit'sa big hassle

Have you used Unisom Sleeptabs (Doxylamine)?

Leave a review
Side effects
4possible side effects
  • Drowsiness
    37%
  • Depression
    7%
  • Abnormal coordination
    6%
  • Loss of full control of bodily movements
    5%
See more detailed side effects
The Unisom Sleeptabs (Doxylamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Sedation, respiratory depression, coma and death
    • Taking with opioids
    • Drinking alcohol
  • Dependence and withdrawal
    • Taking high dosage
    • Taking long-term
    • History of drug abuse
  • Driving impairment
    • Drinking alcohol
    • Taking other medicines that make you less alert
  • Suicidal behavior and ideation
See more detailed risks and warnings
  • Overdosage
    • Using other drugs with similar ingredients
  • Increased side effects
    • Age 65 years or older
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Hyperactivity
    • Children age 6 years or younger
  • Trouble urinating
    • Enlarged prostate
    • History of bladder problems
  • Vision changes
    • Glaucoma
  • Breastfeeding
    • Nursing mothers
See more detailed risks and warnings
Learn more about Klonopin (clonazepam)
Learn more about Unisom Sleeptabs (Doxylamine)