Compare Lamictal vs. Latuda

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Lamictal (Lamotrigine)

Prescription only

Latuda (lurasidone)

Prescription only
Prevents seizures and stabilizes mood.

Lamictal (Lamotrigine) is most useful for treating severe seizure disorders, and for bipolar disorder with more depression symptoms than manic symptoms. Just be careful to increase your dose slowly to avoid skin rash.

3.7/ 5 average rating with 184 reviewsforLamictal
Helps control your thoughts and mood.

Latuda (lurasidone) is good for treating schizophrenia and depression related to bipolar disorder, but can cause sleepiness and movement disorders that can affect your ability to stay alert.

3.8/ 5 average rating with 61 reviewsforLatuda
Upsides
  • Effective at lowering the frequency of seizures in people with epilepsy or Lennox-Gestaut syndrome. Typically used together with other medications for severe seizure disorders.
  • Works best for partial, tonic-clonic, and absence seizures.
  • A first-line treatment for bipolar disorder. Effective long-term treatment for stabilizing mood. Prevents both depressive and manic episodes, but the effect is greater for preventing depression.
  • Doesn't require routine blood tests.
  • Has been shown in clinical studies to help people experience improvement in their thoughts and mood.
  • Can be taken alone or with other medications that manage your mood.
  • Compared to other antipsychotic medicines, Latuda (lurasidone) has a lower risk of causing weight gain, high cholesterol, high blood sugar, and heart rhythm changes.
Downsides
  • Can cause double vision, dizziness, sleepiness, and headache.
  • Has the risk of a rare but life-threatening rash.
  • Can make hormonal birth control less effective.
  • Might be less effective than other medicines for treating manic episodes (acute mania) in people with bipolar disorder.
  • It may take several weeks before you feel the full effects of Latuda (lurasidone).
  • You may get more side effects if you're taking certain antifungal and heart medicines.
  • Can cause you to be more sensitive to heat and make it harder for your body to cool off.
  • Need to avoid drinking alcohol while taking Latuda (lurasidone).
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Used for
Dosage forms
  • Pill
  • Extended release
  • Chewable tablet
  • Dissolving tablet
  • Pill
Price
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Reviews
184 reviews so far
66%
saidit'sworth it
58%
saiditworked well
18%
saidit'sa big hassle

Have you used Lamictal (Lamotrigine)?

Leave a review
61 reviews so far
61%
saidit'sworth it
61%
saiditworked well
25%
saidit'sa big hassle

Have you used Latuda (lurasidone)?

Leave a review
Side effects
36possible side effects
  • Dizziness
    38%
  • Headache
    28%
  • Diplopia
    28%
  • Ataxia
    22%
  • Nausea
    19%
  • Blurred vision
    16%
  • Somnolence
    14%
  • Rhinitis
    14%
  • Pharyngitis
    10%
  • Rash
    10%
  • Vomiting
    9%
  • Cough increased
    8%
  • Flu syndrome
    7%
  • Dysmenorrhea
    7%
  • Fever
    6%
  • Diarrhea
    6%
  • Incoordination
    6%
  • Insomnia
    6%
  • Abdominal pain
    5%
  • Dyspepsia
    5%
  • Constipation
    4%
  • Tremor
    4%
  • Depression
    4%
  • Anxiety
    4%
  • Vaginitis
    4%
  • Convulsion
    3%
  • Irritability
    3%
  • Speech disorder
    3%
  • Pruritus
    3%
  • Vision abnormality
    3%
  • Neck pain
    2%
  • Reaction aggravated (seizure exacerbation)
    2%
  • Anorexia
    2%
  • Arthralgia
    2%
  • Concentration disturbance
    2%
  • Amenorrhea
    2%
See more detailed side effects
12possible side effects
  • Nausea
    14%
  • Sleepiness
    11%
  • Restlessness
    9%
  • Movement disorder
    7%
  • Dry mouth
    5%
  • Vomiting
    4%
  • Diarrhea
    4%
  • Common cold
    4%
  • Anxiety
    4%
  • Flu
    2%
  • Urinary tract infection
    2%
  • Back pain
    2%
See more detailed side effects
Risks and risk factors
  • Suicidal thoughts or behavior
    • History of depression
  • Serious skin rash
    • People also taking Depakote
    • Taking more than the prescribed dose
    • Increasing the dose too quickly
  • Serious allergic reactions
  • Blood disorders
  • Meningitis
  • Interactions with birth control pills
    • Taking birth control pills
  • Withdrawal seizures
    • Stopping Lamictal (Lamotrigine) suddenly
See more detailed risks and warnings
  • Increased risk of death
    • Elderly patients with dementia
  • Suicidal thoughts or behavior
  • Abnormal and involuntary muscle movements
    • Taking Latuda (lurasidone) in higher doses or for a long time
    • Elderly
    • Female
  • Low blood pressure
    • Dehydration
    • Taking blood pressure medications
  • Sedation and driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Low white blood cells
See more detailed risks and warnings