Compare Levemir vs. Glucotrol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Levemir (insulin detemir)

Prescription only

Glucotrol (glipizide)

Prescription only
Lowers blood sugar.

Levemir (insulin detemir) is an effective, long-acting insulin that provides all-day sugar control, but there are similar medications that can be used instead.

3.3/ 5 average rating with 130 reviewsforLevemir
Lowers blood sugar.

Glucotrol (glipizide) is an effective medicine for lowering blood sugar, but it can cause your blood sugar level to be too low so you must always carry some form of sugar with you that can be readily used.

3.2/ 5 average rating with 332 reviewsforGlucotrol
Upsides
  • Insulin is the most effective blood sugar lowering medication, as it lowers A1c (average blood sugar over time) up to 2 or 3%. When used correctly, it'll prevent the harmful effects of high blood sugar levels on your organs and blood vessels.
  • Levemir (insulin detemir) is a long lasting insulin that provides consistent, all-day blood sugar control with less risk of low blood sugar.
  • Doses can be easily adjusted to make a customized regimen that's tailored to your body's needs.
  • Starting insulin early in the treatment of type 2 diabetes can maintain your body's insulin producing cells and slow down disease progression.
  • Levemir (insulin detemir) can be used in people with liver or kidney problems.
  • Lowers A1c levels by 1-2%.
  • Glucotrol (glipizide) is an oral medicine so it might be a good alternative for those who don't like injections.
  • Protects your organs and blood vessels by preventing the harmful effects of high blood sugar levels.
  • Okay to use by people with kidney problems.
  • Available as a generic form and is relatively cheap.
Downsides
  • You have to take Levemir (insulin detemir) by injection.
  • You have to check your blood sugar regularly.
  • There is a risk of low blood sugar episodes with use of Levemir (insulin detemir).
  • Levemir (insulin detemir) can cause tiredness, moderate weight gain, and swelling in your hands, ankles, or feet.
  • Has a higher risk than other diabetes medicine for causing blood sugar levels to be too low.
  • While taking Glucotrol (glipizide), your blood sugars should be checked 2 to 5 times a week, but less often once you are on a stable dose.
  • Can cause mild weight gain of 2-3lb.
  • Might lose its effectiveness over time.
  • Needs to be taken 30 minutes before a meal for it to be most effective.
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Used for
Dosage forms
  • Injection
  • Pill
  • Extended release pill
Price
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Reviews
130 reviews so far
45%
saidit'sworth it
35%
saiditworked well
22%
saidit'sa big hassle

Have you used Levemir (insulin detemir)?

Leave a review
332 reviews so far
50%
saidit'sworth it
32%
saiditworked well
19%
saidit'sa big hassle

Have you used Glucotrol (glipizide)?

Leave a review
Side effects
5possible side effects
  • Upper respiratory tract infection
    26%
  • Headache
    23%
  • Sore throat
    10%
  • Flu-like symptoms
    8%
  • Stomach pain
    6%
See more detailed side effects
9possible side effects
  • Dizziness
    7%
  • Diarrhea
    5%
  • Nervousness
    4%
  • Tremor
    4%
  • Low blood sugar
    3%
  • Constipation
    3%
  • Passing gas
    3%
  • Nausea
    3%
  • Headache
    2%
See more detailed side effects
Risks and risk factors
  • Life-threatening low blood sugar (Hypoglycemia)
    • Insulin dose too high
    • Use of other blood sugar lowering medicines
    • Poor injection techniques
  • Complications due to low potassium
    • Use of other medicine that lower potassium
    • Current electrolyte imbalance
  • Severe allergic reactions
    • Allergy to insulin
See more detailed risks and warnings
  • Serious heart problems
  • Low blood sugar
    • Skipping meals or having inconsistent meal times
    • Drinking alcohol
    • Using other blood sugar-lowering medicine
    • People age 60 or older
    • Those with kidney and/or liver problems
  • Severe allergic reaction
    • History of allergy to sulfa-containing medicine
  • Kidney and liver disease
    • Those with kidney and/or liver disease
  • Breakdown of red blood cells
    • People with G6PD deficiency
See more detailed risks and warnings