Compare Levemir vs. metformin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Levemir (insulin detemir)

Prescription only

Glucophage (metformin)

Prescription only
Lowers blood sugar.

Levemir (insulin detemir) is an effective, long-acting insulin that provides all-day sugar control, but there are similar medications that can be used instead.

3.3/ 5 average rating with 130 reviewsforLevemir
Lowers blood sugar.

Glucophage (metformin) is the first choice medicine to control your blood sugar and lower the risk of death from diabetes, although a few people may not tolerate the stomach side effects.

3.7/ 5 average rating with 938 reviewsformetformin
Upsides
  • Insulin is the most effective blood sugar lowering medication, as it lowers A1c (average blood sugar over time) up to 2 or 3%. When used correctly, it'll prevent the harmful effects of high blood sugar levels on your organs and blood vessels.
  • Levemir (insulin detemir) is a long lasting insulin that provides consistent, all-day blood sugar control with less risk of low blood sugar.
  • Doses can be easily adjusted to make a customized regimen that's tailored to your body's needs.
  • Starting insulin early in the treatment of type 2 diabetes can maintain your body's insulin producing cells and slow down disease progression.
  • Levemir (insulin detemir) can be used in people with liver or kidney problems.
  • Improves sugar control and lowers A1c levels as much as 2%.
  • One of the few diabetes medicines that lowers the risk of death from diabetes-related complications.
  • Doesn't cause weight gain.
  • Rarely causes low blood sugar.
Downsides
  • You have to take Levemir (insulin detemir) by injection.
  • You have to check your blood sugar regularly.
  • There is a risk of low blood sugar episodes with use of Levemir (insulin detemir).
  • Levemir (insulin detemir) can cause tiredness, moderate weight gain, and swelling in your hands, ankles, or feet.
  • Often causes stomach upset, like diarrhea, nausea, gas, or stomach cramping.
  • Usually not a good choice for people with kidney problems. Your doctor will tell you if Glucophage (metformin) is right for you to take.
  • Excessive or chronic alcohol use can increase the risk of a dangerous side effect.
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Used for
Dosage forms
  • Injection
  • Pill
  • Extended release pill
  • Liquid
Price
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Reviews
130 reviews so far
45%
saidit'sworth it
35%
saiditworked well
22%
saidit'sa big hassle

Have you used Levemir (insulin detemir)?

Leave a review
938 reviews so far
65%
saidit'sworth it
46%
saiditworked well
16%
saidit'sa big hassle

Have you used Glucophage (metformin)?

Leave a review
Side effects
5possible side effects
  • Upper respiratory tract infection
    26%
  • Headache
    23%
  • Sore throat
    10%
  • Flu-like symptoms
    8%
  • Stomach pain
    6%
See more detailed side effects
7possible side effects
  • Diarrhea
    53%
  • Nausea/vomiting
    26%
  • Gas
    12%
  • Weakness
    9%
  • Indigestion
    7%
  • Stomach pain
    6%
  • Headache
    6%
See more detailed side effects
Risks and risk factors
  • Life-threatening low blood sugar (Hypoglycemia)
    • Insulin dose too high
    • Use of other blood sugar lowering medicines
    • Poor injection techniques
  • Complications due to low potassium
    • Use of other medicine that lower potassium
    • Current electrolyte imbalance
  • Severe allergic reactions
    • Allergy to insulin
See more detailed risks and warnings
  • Excess lactic acid in the blood
    • Kidney problems
    • Liver problems
    • Congestive heart failure
    • Using contrast dye for procedures
    • Surgery
    • Alcohol use
  • Low vitamin B12 levels
See more detailed risks and warnings