Compare Lexapro vs. Anafranil
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Improves mood and helps you relax.
Lexapro (escitalopram) is good for treating depression and anxiety. It is less likely to cause side effects than and has fewer drug interactions. However, it might not be a good choice if you have liver or heart problems.
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3.6/ 5 average rating with 1063 reviewsforLexapro
Helps control obsessive or compulsive behaviors.
Anafranil (clomipramine) effectively treats obsessive-compulsive disorder (OCD), but has potentially intolerable side effects.
Upsides
- Effective at relieving depression and anxiety symptoms.
- Lowers the likelihood that your depression will come back.
- Lexapro (escitalopram) has less drug interactions than other similar antidepressants and might cause fewer side effects.
- Anafranil (clomipramine) can help with falling sleep.
- Anafranil (clomipramine) has a lower risk of causing heart problems compared to other medications like it.
- Safe to use by children.
Downsides
- Can cause a small weight gain of 1-5 pounds.
- Lexapro (escitalopram) is not a good option if you have heart or liver problems.
- The first antidepressant you try might not always work, so you may need to try a few different medicines until you find one that works for you.
- Anafranil (clomipramine) is more likely to cause side effects than other medications for OCD.
- Anafranil (clomipramine) can affect sexual performance for men.
- It is not recommended for the elderly because it can cause fainting and falls.
Used for
Dosage forms
- Pill
- Liquid
- Pill
Price
Lowest price
$7.94
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$78.31
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Reviews
1063 reviews so far
61%
saidit'sworth it
48%
saiditworked well
15%
saidit'sa big hassle
Have you used Lexapro (escitalopram)?
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Side effects
25possible side effects
- Headache24%
- Nausea18%
- Problems ejaculating14%
- Sleepiness13%
- Insomnia12%
- Dry mouth9%
- Diarrhea8%
- Fatigue8%
- Decreased libido7%
- Problems with orgasm6%
- Constipation5%
- Flu-like symptoms5%
- Increased sweating4%
- Indigestion3%
- Vomiting3%
- Neck/shoulder pain3%
- Abnormal dreams3%
- Decrease appetite3%
- Lack of energy3%
- Tingling or burning in the hands/feet2%
- Abdominal pain2%
- Flatulence2%
- Toothache2%
- Yawning2%
- Menstrual disorder2%
109possible side effects
- Dry mouth84%
- Sleepiness54%
- Tremor54%
- Dizziness54%
- Headache52%
- Constipation47%
- Ejaculation failure42%
- Fatigue39%
- Nausea33%
- Increased sweating28%
- Insomnia25%
- Upset stomach22%
- Loss of appetite22%
- Sex drive changes21%
- Impotence20%
- Nervousness18%
- Weight increase18%
- Abnormal vision18%
- Sore throat14%
- Urinary problems14%
- Muscle contractions13%
- Diarrhea13%
- Joint pain13%
- Abdominal pain13%
- Runny nose12%
- Menstrual cramps12%
- Increased appetite11%
- Burning/prickling skin sensation9%
- Memory problems9%
- Anxiety9%
- Sleep disorder9%
- Rash8%
- Flushing8%
- Changes in taste8%
- Twitching7%
- Vomiting7%
- Memory impairment7%
- Chest pain7%
- Allergy7%
- Weight decrease7%
- Asthma attacks7%
- Urinary retention7%
- Itching of the skin6%
- Gas6%
- Changes in blood pressure6%
- Stuffy nose6%
- Coughing6%
- Urinary tract infection6%
- Ringing in the ears6%
- Back pain6%
- Impaired concentration5%
- Depression5%
- Tooth disorder5%
- Hot flushes5%
- Increased urination5%
- Increased muscle tone4%
- Fever4%
- Palpitation4%
- Fast heartbeat4%
- Unusual milk production4%
- Menstrual disorder4%
- Pain4%
- Ear infections4%
- Changes in heartbeat4%
- Psychosomatic disorder3%
- Yawning3%
- Confusion3%
- Speech disorder3%
- Abnormal dreaming3%
- Agitation3%
- Migraine3%
- Excess tearing3%
- Social detachment2%
- Irritability2%
- Mood swings2%
- Skin irritation2%
- Acne2%
- Dry skin2%
- Gastrointestinal disorder2%
- Difficulty swallowing2%
- Local swelling2%
- Chills2%
- Nose bleed2%
- Painful urination2%
- Bladder pain2%
- Vaginal itching2%
- Increased vaginal discharge2%
- Breast enlargement2%
- Pupil dilation2%
- Thirst2%
- Muscle twitching2%
- Tingling or burning sensation2%
- Hypertonia2%
- Panic reaction2%
- Aggressive reaction2%
- Muscle weakness2%
- Abnormal skin odor2%
- Excessive burping2%
- Sores around the mouth2%
- Lack of energy2%
- Bad breath2%
- Fainting2%
- Dyspnea2%
- Laryngitis2%
- Changes in pupils2%
- Eyelid twitching2%
- Eye allergies2%
- Balance problems2%
- Anemia2%
Risks and risk factors
- Suicidal thoughts or behavior
- Age 24 years or younger
- Serotonin syndrome
- Using other medications that affect serotonin
- Withdrawal
- Stopping Lexapro (escitalopram) suddenly
- Increased bleeding
- Taking blood thinners
- Sexual problems
- Uncovering of bipolar disorder
- Bipolar disorder
- Suicidal thoughts or behavior
- Age 24 years or younger
- Serotonin syndrome
- Antidepressants
- Lithium
- Triptans
- St. John's wort
- Fentanyl
- Tramadol
- MAO inhibitors
- Seizures
- History of seizure
- Taking other medicines that increase seizure risk
- Brain damage
- Alcoholism
- Withdrawal symptoms
- Stopping Anafranil (clomipramine) suddenly
- Low blood pressure
- Age 65 years or older
- Eye problems