Compare Lialda vs. Asacol

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Lialda (mesalamine)

Prescription only

Lialda (Mesalamine)

Prescription only
Treats ulcerative colitis and helps prevent flares from coming back.

Lialda (mesalamine) effectively reduces symptoms of mild-to-moderate ulcerative colitis, and may be less irritating than other formulations, but is brand only, so may be more expensive..

Treats inflammatory bowel disease.

Lialda (Mesalamine) is an effective first-line medicine for inflammatory bowel disease. There isn't a generic version and you'll have to take it multiple times a day.

Upsides
  • Lialda (mesalamine) effectively treats and helps maintain remission of ulcerative colitis.
  • Often used as a first-choice treatment.
  • Since Lialda (mesalamine) is a delayed release form, the pill is taken only once a day compared to other similar medicines and may be less irritating to the stomach and intestines.
  • Available as a generic.
  • Effective first-line medication for treating and lowering the symptoms of mild inflammatory bowel disease.
  • About half the people who have mild to moderate colon inflammation and take Lialda (Mesalamine) will see improvement.
  • Available in tablets, capsules, enemas, and suppositories.
  • Certain forms of Lialda (Mesalamine) can be used during pregnancy. Talk to your doctor if you're pregnant, or plan on becoming pregnant, and you want to take Lialda (Mesalamine).
Downsides
  • Treatment dosage must be taken once a day for a total of 8 weeks.
  • Can take a few weeks before you start to feel the effects.
  • Combination therapy with oral and rectal forms may be needed for some people.
  • No generic versions are available for the tablets, capsules, and suppositories (meaning it could be somewhat expensive).
  • Doesn't work well for severe colon inflammation.
  • You may need to take Lialda (Mesalamine) three or four times a day.
  • Not a good option if you have kidney disease.
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Used for
Dosage forms
  • Delayed-release pill
  • Pill
  • Extended release
  • Enema
  • Suppository
Price
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Reviews
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Side effects
5possible side effects
  • Ulcerative colitis
    6%
  • Headache
    3%
  • Abnormal liver tests
    2%
  • Abdominal pain
    2%
  • Diarrhea
    2%
See more detailed side effects
35possible side effects
  • Headache
    35%
  • Abdominal pain
    18%
  • Eructation
    16%
  • Pain
    14%
  • Nausea
    13%
  • Pharyngitis
    11%
  • Dizziness
    8%
  • Asthenia
    7%
  • Diarrhea
    7%
  • Back pain
    7%
  • Fever
    6%
  • Rash
    6%
  • Dyspepsia
    6%
  • Rhinitis
    5%
  • Arthralgia
    5%
  • Hypertonia
    5%
  • Vomiting
    5%
  • Constipation
    5%
  • Flatulence
    3%
  • Dysmenorrhea
    3%
  • Chest pain
    3%
  • Chills
    3%
  • Flu syndrome
    3%
  • Peripheral edema
    3%
  • Myalgia
    3%
  • Sweating
    3%
  • Colitis exacerbation
    3%
  • Pruritus
    3%
  • Adverse events
    3%
  • Acne
    2%
  • Increased cough
    2%
  • Malaise
    2%
  • Arthritis
    2%
  • Conjunctivitis
    2%
  • Insomnia
    2%
See more detailed side effects
Risks and risk factors
  • Kidney problems
    • Preexisting kidney problems
    • Taking medications toxic to the kidney
  • Liver problems
    • Preexisting liver problems
    • Taking other medications toxic to the liver
  • Serious allergic reactions
    • Sulfasalazine reaction
    • Allergy to salicylates (aspirin)
  • Abnormal reaction to Lialda (mesalamine)
  • Upper gastrointestinal tract blockage
  • Drug & disease precautions
See more detailed risks and warnings
  • Serious allergic reactions
    • Asthma
    • Rhinitis
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy
  • Serious allergic reactions
    • Phenylketonuria (PKU)
  • Worsening kidney or liver function
    • Kidney problems
    • Liver problems
  • Blood disorders
    • Age 65 or older
  • Liver toxicity
    • Liver problems
  • Worsening of colitis
    • Taking Lialda (Mesalamine) at the start of treatment
See more detailed risks and warnings