Compare Lisinopril vs. felodipine

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Zestril (lisinopril)

Prescription only

Plendil (felodipine)

Prescription only
Lowers blood pressure.

Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.

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3.8/ 5 average rating with 687 reviewsforLisinopril
Lowers blood pressure.

Plendil (felodipine) works well to lower blood pressure, but it may cause swelling in your arms and legs at higher doses.

Upsides
  • A first-choice blood pressure treatment for many people.
  • Lowers the risk of heart attack and stroke.
  • Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
  • Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
  • Very cheap drug, and comes available as a liquid for children over 6 years of age.
  • Plendil (felodipine) is a good option for people with high blood pressure.
  • Calcium channel blockers sometimes work better for people of African descent than other blood pressure lowering drugs.
Downsides
  • Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
  • Requires a yearly blood test to see how the medicine is affecting your body.
  • Zestril (lisinopril) isn't safe to use if you're pregnant.
  • Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
  • Plendil (felodipine) may not work as well as other calcium channel blockers.
  • It can lead to more swelling in your arms and legs when taken at higher doses.
  • You can't miss doses. Stopping Plendil (felodipine) could cause a sudden spike in blood pressure.
  • Plendil (felodipine) can't be crushed or cut into two.
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Used for
Dosage forms
  • Pill
  • Liquid
  • Extended release
Price
Lowest price
$497.46
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Lowest price
$22.85
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Reviews
687 reviews so far
61%
saidit'sworth it
51%
saiditworked well
14%
saidit'sa big hassle

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Side effects
1possible side effects
  • Low blood pressure
    5%
See more detailed side effects
8possible side effects
  • Headache
    10%
  • Swelling
    9%
  • Flushing
    5%
  • Racing heart beat
    4%
  • Weakness
    3%
  • Dizziness
    3%
  • Nausea
    2%
  • Colds or flu
    2%
See more detailed side effects
Risks and risk factors
  • Harm to fetus
    • Women of childbearing age
  • Cough
  • Swelling of face and head
    • African descent
  • High potassium
    • Current kidney problems
    • Medicines that increase potassium
    • Use of salt substitutes
  • Worsening kidney problems
    • History of kidney problems
  • Low blood pressure
    • Taking with alcohol
    • Taking other medicines that lower your blood pressure
See more detailed risks and warnings
  • Low blood pressure
    • Over age 65
  • Heart failure
    • Taking in combination with a beta-blocker
  • Special dosing requirements
    • Liver disease
    • Over age 65
  • Swelling in arms and legs
    • History of heart failure
    • History of kidney disease
See more detailed risks and warnings
Learn more about Zestril (lisinopril)
Learn more about Plendil (felodipine)