Compare Lisinopril vs. Zestoretic
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood pressure.
Zestril (lisinopril) is a good blood pressure-lowering medicine that protects kidney function.
●●●●●
3.8/ 5 average rating with 687 reviewsforLisinopril
Lowers blood pressure.
Lisinopril/hydrochlorothiazide is a good 2-in-1 blood pressure-lowering medicine that protects kidney function.
●●●●●
3.4/ 5 average rating with 294 reviewsforZestoretic
Upsides
- A first-choice blood pressure treatment for many people.
- Lowers the risk of heart attack and stroke.
- Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
- Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
- Very cheap drug, and comes available as a liquid for children over 6 years of age.
- Combination medicine for people with high blood pressure. Doctors might prescribe it when you need more than one medicine to control your blood pressure.
- The two drugs in Lisinopril/hydrochlorothiazide work together to lower blood pressure, remove extra water from your body, and lower your risk of heart attack and stroke.
- Protects kidney function, which is especially useful for people with diabetes or mild-to-moderate kidney disease.
- Recommended for anyone with heart failure since it lowers the risk of death and further damage to your heart.
Downsides
- Up to 10% of people can get a dry cough while using this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
- Requires a yearly blood test to see how the medicine is affecting your body.
- Zestril (lisinopril) isn't safe to use if you're pregnant.
- Doesn't work as well in people of African descent, and can cause a greater chance of face, tongue, or lip swelling.
- Comes in fixed dosage strengths, so it's harder for your doctor to adjust your dose.
- Up to 1 in 10 people can get a dry cough with this medicine. It ranges from a mild tickle in the throat to a persistent hacking cough.
- Makes you urinate more often.
- Doesn't work as well in people with severe kidney problems.
- Requires a yearly blood test to see how the medicine is affecting your body.
- Not safe to use if you're pregnant.
Used for
Dosage forms
- Pill
- Liquid
- Pill
Price
Lowest price
$497.46
Find instant savings near youLowest price
$8.75
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
687 reviews so far
61%
saidit'sworth it
51%
saiditworked well
14%
saidit'sa big hassle
Have you used Zestril (lisinopril)?
Leave a review294 reviews so far
51%
saidit'sworth it
40%
saiditworked well
17%
saidit'sa big hassle
Have you used Zestoretic (Lisinopril / Hydrochlorothiazide)?
Leave a reviewSide effects
11possible side effects
- Dizziness8%
- Headache5%
- Cough4%
- Fatigue4%
- Orthostatic Effects3%
- Diarrhea3%
- Nausea2%
- Upper Respiratory Infection2%
- Muscle Cramps2%
- Asthenia2%
- Paresthesia2%
Risks and risk factors
- Harm to fetus
- Women of childbearing age
- Cough
- Swelling of face and head
- African descent
- High potassium
- Current kidney problems
- Medicines that increase potassium
- Use of salt substitutes
- Worsening kidney problems
- History of kidney problems
- Low blood pressure
- Taking with alcohol
- Taking other medicines that lower your blood pressure
- Harm to fetus
- Women of childbearing age
- Unusual tongue swelling
- African descent
- Severe allergic reactions while on dialysis
- People requiring high flux dialysis
- Acute kidney failure
- History of kidney disease
- Heart problems due to high potassium
- Current kidney problems
- Medicine that increase potassium
- Use of salt substitute
- Cough