Compare loxapine vs. Seroquel
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats schizophrenia.
Loxitane (loxapine) is not recommended as a first choice medicine for treatment of schizophrenia, but it can be good if other medicines haven't worked because of bad side effects.
Helps control your thoughts and mood.
Seroquel (quetiapine) is a effective at treating schizophrenia, mania, and depression but it can cause weight gain and high blood glucose levels.
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3.7/ 5 average rating with 250 reviewsforSeroquel
Upsides
- Loxitane (loxapine) can be used to control schizophrenia if other medicines haven't worked because you don't like their side effects.
- Loxitane (loxapine) is available as a generic.
- Seroquel (quetiapine) is effective at relieving psychotic symptoms and manic episodes.
- Seroquel (quetiapine) has fewer side effects than most antipsychotic medications.
- Seroquel (quetiapine) is less likely to cause heart problems compared to some other antipsychotics.
- Seroquel (quetiapine) is also the least likely to cause Extrapyramidal Symptoms (EPS) – a movement disorder that causes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
Downsides
- Loxitane (loxapine) is not recommended as a first choice for treating schizophrenia because it's more likely to cause trouble with controlling movements.
- Loxitane (loxapine) can stop vomiting, so it can be difficult to tell if someone's overdosed on drugs.
- Loxitane (loxapine) can raise heart rate and lower blood pressure.
- Seroquel (quetiapine) has a moderate to high risk of weight gain, elevated cholesterol and/or blood sugar compared to other antipsychotics.
- You might need routine blood tests to check how Seroquel (quetiapine) is affecting your body.
Used for
- Schizophrenia
- Depression with psychosis
Dosage forms
- Pill
- Pill
- Extended release
Price
Lowest price
$18.37
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$20.79
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Reviews
Not enough review data.Leave a review
250 reviews so far
56%
saidit'sworth it
50%
saiditworked well
27%
saidit'sa big hassle
Have you used Seroquel (quetiapine)?
Leave a reviewSide effects
The Loxitane (loxapine) FDA package insert doesn’t have numbers about how common side effects are.
36possible side effects
- Drowsiness34%
- Dry mouth19%
- Headache17%
- Weakness10%
- Constipation10%
- Dizziness9%
- Tremor8%
- Stomach pain7%
- Low blood pressure7%
- Agitation6%
- Weight gain6%
- Sore throat6%
- Back pain5%
- Stiffness/difficulty moving4%
- Hay fever4%
- Swelling in the limbs4%
- Twitching4%
- Indigestion4%
- Depression3%
- Lazy eye3%
- Speech disorder3%
- Altered hormone levels3%
- Heaviness2%
- Infection2%
- Fever2%
- High blood pressure2%
- Increased heart rate2%
- Increased appetite2%
- Hypothyroidism2%
- Incoordination2%
- Abnormal thinking2%
- Anxiety2%
- Loss of control of movements2%
- Sinus infection2%
- Sweating2%
- Urinary Tract Infection2%
Risks and risk factors
- Higher risk of death
- People age 65 and older with dementia and psychosis
- Difficulty controlling movements
- Neuroleptic malignant syndrome
- Taking antipsychotic medications
- Seizures
- History of seizures
- Vision changes
- Higher risk of death
- Elderly patients with dementia-related psychosis
- Suicidal thoughts or behavior
- Children, adolescents, and young adults (<24 years old)
- Neuroleptic malignant syndrome
- Heart problems
- History of heart problems
- Drug interactions
- Extrapyramidal Symptoms (EPS)
- Metabolic changes (increased blood sugar, high cholesterol and weight gain)
- People with diabetes
- People with high cholesterol