Compare Lunesta vs. Unisom
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Helps you sleep.
Lunesta (Eszopiclone) is good for falling asleep and staying asleep. Not as habit-forming as some sleep medicines, but more likely to cause withdrawal symptoms if you stop suddenly.
●●●●●
3.3/ 5 average rating with 592 reviewsforLunesta
Treats allergy symptoms and helps you sleep.
Unisom Sleeptabs (Doxylamine) can help you get a good night's sleep, but you can have a hard time waking up if you don't give yourself enough time to sleep.
●●●●●
3.3/ 5 average rating with 585 reviewsforUnisom
Upsides
- Effective at helping people fall asleep faster and sleep longer.
- Not as habit-forming, so you can use it for longer than most other sleep medicines.
- Works well to help you fall asleep and doesn't make you feel groggy the next morning.
- Has fewer side effects than prescription sleep aid medications.
- Available over the counter without a prescription.
- Not habit-forming like other sleep aids can be.
Downsides
- More likely to cause withdrawal symptoms if you stop taking it suddenly.
- Might not be safe if you have a history of drug or alcohol abuse, depression, lung disease, or a condition that affects metabolism.
- It's easy to become reliant on sleep medicines. In the long run, it's better to learn good sleeping habits and behavior so that you can sleep better naturally.
- Shouldn't be used unless you have a full night to sleep.
- You shouldn't drive after taking Unisom Sleeptabs (Doxylamine) until you know how it affects you.
- Drinking alcohol while taking Unisom Sleeptabs (Doxylamine) isn't recommended.
- It can increase the risk of falls, so elderly people shouldn't use Unisom Sleeptabs (Doxylamine).
Used for
Dosage forms
- Pill
- Pill
- Chewable tablet
- Liquid
Price
Lowest price
$12.67
Find instant savings near youLowest price
$6.47
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
592 reviews so far
55%
saidit'sworth it
36%
saiditworked well
17%
saidit'sa big hassle
Have you used Lunesta (Eszopiclone)?
Leave a review585 reviews so far
58%
saidit'sworth it
32%
saiditworked well
11%
saidit'sa big hassle
Have you used Unisom Sleeptabs (Doxylamine)?
Leave a reviewSide effects
10possible side effects
- Headache15%
- Unpleasant Taste8%
- Dyspepsia6%
- Pain4%
- Diarrhea4%
- Pruritus4%
- Dry Mouth3%
- Abnormal Dreams3%
- Neuralgia3%
- Urinary Tract Infection3%
The Unisom Sleeptabs (Doxylamine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Dependence and withdrawal
- Continuous use for 2 weeks or more
- Driving impairment
- Alcohol
- Taking other medicines that make you less alert
- Less than 7 hours of sleep.
- Abnormal thoughts
- Undiagnosed psychiatric conditions
- Sleep driving
- Taking with alcohol or drugs that acts in the brain
- Serious allergic reactions
- Risk of falls and injury
- Elderly
- Higher dose
- Liver problems
- Taking Lunesta (Eszopiclone) with other nervous system depressants
- Long-term use
- Risk to fetus
- Women of childbearing age
- Breast-feeding
- Overdosage
- Using other drugs with similar ingredients
- Increased side effects
- Age 65 years or older
- Driving impairment
- Taking with alcohol
- Taking other medicines that make you less alert
- Hyperactivity
- Children age 6 years or younger
- Trouble urinating
- Enlarged prostate
- History of bladder problems
- Vision changes
- Glaucoma
- Breastfeeding
- Nursing mothers