Compare meloxicam vs. Diclofenac

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Mobic (meloxicam)

Prescription only

Zorvolex (Diclofenac)

Prescription only
Relieves pain and inflammation.

Mobic (meloxicam) works well for pain and inflammation and you only take it once a day, but you need a prescription.

3.8/ 5 average rating with 141 reviewsformeloxicam
Treats arthritis pain and swelling.

Zorvolex (Diclofenac) is an okay medication used to treat pain and swelling caused by arthritis. However, because of the risk of heart attack, you should limit the amount you take.

Upsides
  • Taken only once a day, while other NSAIDS need to be taken a few times a day for the same effect.
  • Works well to relieve pain and inflammation due to osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
  • Causes less stomach upset than other NSAIDs.
  • Relatively cheap compared to other prescription NSAIDS.
  • Clinical studies show that Zorvolex (Diclofenac) is better at relieving arthritis pain than acetaminophen (Tylenol).
  • Can be used as needed to treat pain and swelling.
  • Available as a generic.
Downsides
  • Mobic (meloxicam) does not kick in as fast as other NSAIDS.
  • It's available by prescription only.
  • Mobic (meloxicam) is not as safe as other alternatives for pregnant women and people who are age 60 or older.
  • It can cause serious complications like stomach bleeding and kidney problems if taken for a long time.
  • You should avoid alcohol while on Zorvolex (Diclofenac) since it can increase your risk of stomach issues.
  • If you're taking it on a regular basis, you'll need to get labs done to make sure your liver and kidneys aren't being affected.
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Used for
Dosage forms
  • Pill
  • Suspension
  • Pill
Price
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Reviews
141 reviews so far
64%
saidit'sworth it
54%
saiditworked well
13%
saidit'sa big hassle

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Side effects
15possible side effects
  • Indigestion
    10%
  • Upper respiratory tract infection
    8%
  • Nausea
    7%
  • Urinary tract infection
    7%
  • Pain
    5%
  • Abdominal pain
    3%
  • Constipation
    3%
  • Diarrhea
    3%
  • Gas
    3%
  • Vomiting
    3%
  • Dizziness
    3%
  • Headache
    3%
  • Anemia
    3%
  • Swelling
    2%
  • Insomnia
    2%
See more detailed side effects
28possible side effects
  • Upper respiratory tract infection
    8%
  • Headache
    8%
  • Nausea
    7%
  • Urinary tract infection
    7%
  • Diarrhea
    6%
  • Nasopharyngitis
    6%
  • Constipation
    5%
  • Sinusitis
    5%
  • Osteoarthritis
    5%
  • Cough
    4%
  • Alanine aminotransferase increased
    4%
  • Abdominal pain upper
    3%
  • Vomiting
    3%
  • Back pain
    3%
  • Dyspepsia
    3%
  • Procedural pain
    3%
  • Bronchitis
    3%
  • Hypertension
    3%
  • Influenza
    3%
  • Arthralgia
    3%
  • Contusion
    3%
  • Blood creatinine increased
    2%
  • Flatulence
    2%
  • Abdominal discomfort
    2%
  • Aspartate aminotransferase increased
    2%
  • Dizziness
    2%
  • Fall
    2%
  • Abdominal pain
    2%
See more detailed side effects
Risks and risk factors
  • Heart attack and stroke
    • History of heart problems
    • Taking the medicine for a long period of time
  • Stomach bleeding
    • History of stomach bleeding
    • Age 60 or older
    • Taking aspirin, other NSAIDs, or blood thinners
    • Drinking more than 3 alcoholic beverages a day
    • Smoking
    • Taking the medicine for a long time
  • Severe allergic reaction
    • Asthma
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy
  • Kidney damage
    • Kidney disease
    • Heart failure
    • Liver disease
    • Taking certain high blood pressure medications
    • Age 60 or older
    • Taking the medicine for a long period of time
  • Harm to fetus (unborn baby)
    • Women who want to or can become pregnant
    • Pregnant women
See more detailed risks and warnings
  • Heart attack or stroke
    • History of heart problems
    • High blood pressure
    • High cholesterol
    • Diabetes
    • Being overweight or obese
    • Smoking
  • Stomach bleeding
    • History of stomach bleeding or ulcers
    • Age 65 years or older
  • Bruising or bleeding
    • Bleeding disorder
    • Taking other blood-thinning medications
  • Serious allergic reactions
    • Asthma
    • Rhinitis
    • Nasal polyps
    • Aspirin allergy
    • NSAID allergy
  • Lowers kidney function
    • Kidney problems
    • Heart failure
    • Liver disease
    • Taking diuretics
    • Taking ACE inhibitors or angiotensin receptor blockers (ARBs)
    • Age 65 or older
  • Increased blood pressure
    • History of high blood pressure
    • Taking water pills (diuretics)
See more detailed risks and warnings