Compare methotrexate vs. Arava
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Reduces inflammation and cell replication.
Otrexup (methotrexate) is the first-choice treatment for many types of cancer and arthritis, but it has many side effects.
No information currently available
Upsides
- Otrexup (methotrexate) is available as an affordable generic form.
- Otrexup (methotrexate) comes as a tablet, an injection that you give yourself, or an infusion that you get in the doctor's office or infusion center.
No information currently available
Downsides
- You may need frequent blood tests for monitoring when taking Otrexup (methotrexate).
- Otrexup (methotrexate) can cause serious birth defects so women should avoid getting pregnant for at least 6 month and men 3 months after taking it.
- While on Otrexup (methotrexate), you should avoid alcohol and staying out in the sun for too long.
No information currently available
Used for
- Cancer
- Juvenile arthritis
- Rheumatoid arthritis
- Psoriasis
- Crohn disease
- Lupus
- Rheumatoid arthritis
- Crohn's disease Juvenile rheumatoid arthritis Psoriatic arthritis
Dosage forms
- Pill
- Injection
- Liquid
- Pill
Price
Lowest price
$434.59
Find instant savings near youLowest price
$29.74
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
Not enough review data.Leave a review
Not enough review data.Leave a review
Side effects
4possible side effects
- Abnormal liver function tests14%
- Nausea, vomiting, diarrhea11%
- Mouth inflammation and sores2%
- Low white blood count2%
The Arava (Leflunomide) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Bone marrow suppression
- Worsening side-effects
- Reduced kidney function
- fluid in the abdomen
- fluid in the lungs
- Use of NSAIDs
- NSAIDS
- High dose of methotrexate
- Liver problems
- Long-term use
- Psoriasis
- Lung problems
- Diarrhea and mouth sores
- Taking Otrexup (methotrexate) with high-dose NSAIDs
- Tumor lysis syndrome
- Rapidly growing tumors
- Skin reactions
- Infections
- White blood cell cancer
- Skin and bone tissue deterioration
- Radiotherapy
No information currently available