Compare minocycline vs. Bactrim

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats bacterial infections.

Solodyn (minocycline) is effective in treating a variety of bacterial infections such as acne, but it can cause permanent tooth staining, especially in an unborn baby and those who are age 8 or younger.

4.0/ 5 average rating with 17 reviewsforminocycline
Kills bacteria.

Bactrim (sulfamethoxazole / trimethoprim) is good for treating many bacterial infections and is available as a generic. However, you can be more likely to sunburn.

3.6/ 5 average rating with 473 reviewsforBactrim
Upsides
  • May be taken with or without food.
  • Solodyn (minocycline) is used in combination with other medications to treat severe acne.
  • Available as a generic form.
  • Solodyn (minocycline) is less likely to cause sunburn than other tetracycline antibiotics.
  • Can be a good alternative treatment for certain infections when penicillin can't be used.
  • Widely available as a generic product and in a variety of formulations (tablet, capsule, suspension).
  • Works well to treat many types of bacterial infections
Downsides
  • It can make birth control pills less effective, so barrier methods of birth control like condoms or diaphragms should be used while on Solodyn (minocycline).
  • Can permanently discolor your teeth, mouth, gums and skin. This is more common for pregnant women in their last half of pregnancy, infants, and children 8 and younger.
  • Your skin may be more sensitive to the sun and your chances of getting sunburned are higher.
  • May cause dizziness and affect your driving ability.
  • Not a good option for pregnant women since it can slow down the bone development of a fetus (unborn baby).
  • Makes you sensitive to the sun.
  • Can upset your stomach
  • Drink plenty of water or fluids to avoid harming your kidneys
  • May cause birth defects
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Used for
Dosage forms
  • Pill
  • Extended-release pill
  • Pill
  • Liquid
Price
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Reviews
17 reviews so far
53%
saidit'sworth it
59%
saiditworked well
18%
saidit'sa big hassle

Have you used Solodyn (minocycline)?

Leave a review
473 reviews so far
59%
saidit'sworth it
49%
saiditworked well
22%
saidit'sa big hassle

Have you used Bactrim (sulfamethoxazole / trimethoprim)?

Leave a review
Side effects
The Solodyn (minocycline) FDA package insert doesn’t have numbers about how common side effects are.
The Bactrim (sulfamethoxazole / trimethoprim) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Yellowing of teeth
    • Age 8 or younger
    • Women in their last half of pregnancy
    • Infants
    • Using Solodyn (minocycline) for a long period of time
  • Decreased effectiveness of oral birth control pills
    • Using oral birth control pills
  • New infection
    • Using Solodyn (minocycline) for a long period of time
  • Sunburn
  • Harm to fetus (unborn baby)
    • Women who can potentially or want to become pregnant
    • Pregnant women
See more detailed risks and warnings
  • Diarrhea
  • Sunburn
  • Rash
  • Harm to fetus
  • Lower kidney function
    • Elderly
    • Taking other medicines that lower kidney function
See more detailed risks and warnings