Compare Minocycline vs. Bactrim

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Treats bacterial infections.

Solodyn (Minocycline) is an effective way to treat certain skin infections, acne, and rosacea, but you'll need to use barrier methods of birth control since it can make birth control pills less effective and cause birth defects.

4.0/ 5 average rating with 17 reviewsforMinocycline
Kills bacteria.

Bactrim (sulfamethoxazole / trimethoprim) is good for treating many bacterial infections and is available as a generic. However, you can be more likely to sunburn.

3.6/ 5 average rating with 473 reviewsforBactrim
Upsides
  • Clinical studies show it's effective against MRSA, a common skin infection, and it's commonly used to treat acne and rosacea.
  • Available as a generic, so it should be reasonably priced.
  • Solodyn (Minocycline) is less likely to cause sunburn than other tetracycline antibiotics.
  • Bacteria are less likely to become resistant to Solodyn (Minocycline) than other tetracycline antibiotics.
  • Widely available as a generic product and in a variety of formulations (tablet, capsule, suspension).
  • Works well to treat many types of bacterial infections
Downsides
  • It can make birth control pills less effective, so people should use barrier methods of birth control like condoms or diaphragms while on Solodyn (Minocycline).
  • Can stain your teeth, mouth, and gums if you're using the tablets, or your skin if you're using the topical version, but this is temporary.
  • Makes you sensitive to the sun.
  • Can upset your stomach
  • Drink plenty of water or fluids to avoid harming your kidneys
  • May cause birth defects
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Used for
Dosage forms
  • Pill
  • Extended release
  • Extended release capsule
  • Pill
  • Liquid
Price
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Reviews
17 reviews so far
53%
saidit'sworth it
59%
saiditworked well
18%
saidit'sa big hassle

Have you used Solodyn (Minocycline)?

Leave a review
473 reviews so far
59%
saidit'sworth it
49%
saiditworked well
22%
saidit'sa big hassle

Have you used Bactrim (sulfamethoxazole / trimethoprim)?

Leave a review
Side effects
The Solodyn (Minocycline) FDA package insert doesn’t have numbers about how common side effects are.
The Bactrim (sulfamethoxazole / trimethoprim) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Changes in teeth
    • Age 8 years or younger
  • Decreased effectiveness of birth control pills
    • Using oral birth control pills
  • Diarrhea from a superinfection (an infection that happens after, or in addition to, an earlier infection)
    • Long antibiotic treatment period
  • Rash
  • Sunburn
  • Harm to fetus
    • Women of childbearing age
See more detailed risks and warnings
  • Diarrhea
  • Sunburn
  • Rash
  • Harm to fetus
  • Lower kidney function
    • Elderly
    • Taking other medicines that lower kidney function
See more detailed risks and warnings