Compare Mirapex vs. Eldepryl

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Mirapex (pramipexole)

Prescription only

Eldepryl (selegiline)

Prescription only
Helps with movement problems.

Mirapex (pramipexole) is effective for Parkinson's disease or restless legs syndrome, but can cause extreme drowsiness that affects daily living.

Treats Parkinson's disease.

Used with other medicines for Parkinson's disease to boost its effect.

Upsides
  • Mirapex (pramipexole) may be better for older people with Parkinson's since it causes fewer movement and mental changes than its alternatives.
  • Mirapex (pramipexole) comes in extended-release form to help reduce side effects and ease administration.
  • Available as a generic so it will be cheaper than similar brand medications.
  • There are two different versions of Eldepryl (selegiline), a quick dissolving tablet and a regular tablet.
  • Eldepryl (selegiline) is one of the recommended medicines you can take along with carbidopa/levodopa if your Parkinson's disease is getting worse.
Downsides
  • Mirapex (pramipexole) can be used by itself, but is usually used in combination with other medications to treat Parkinson's.
  • Not the best choice if you have kidney problems.
  • You cannot suddenly stop taking Mirapex (pramipexole) if you have been taking it for a long time.
  • You may have to limit the amount of cheese, smoked meat, and soy sauce you eat while taking Eldepryl (selegiline) since it can raise your blood pressure.
  • Can keep you up at night if you take it later in the day
  • Doesn't work by itself to treat Parkinson's disease.
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Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Dissolving tablet
Price
Lowest price
$2029.23
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Reviews
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Side effects
36possible side effects
  • Postural hypotension
    53%
  • Muscle rigidity
    47%
  • Extrapyramidal syndrome
    28%
  • Insomnia
    27%
  • Dizziness
    26%
  • Hallucinations
    17%
  • Accidental injury
    17%
  • Dream abnormalities
    11%
  • Confusion
    10%
  • Muscle weakness
    10%
  • Constipation
    10%
  • Sleepiness
    9%
  • Muscle problems
    8%
  • Gait abnormalities
    7%
  • Muscle tenseness
    7%
  • Dry mouth
    7%
  • Memory loss
    6%
  • Urinary frequency
    6%
  • General swelling
    4%
  • Urinary tract infection
    4%
  • Shortness of breath
    4%
  • Accomodation abnormalities
    4%
  • Restlessness
    3%
  • Thinking abnormalities
    3%
  • Chest pain
    3%
  • Malaise
    3%
  • Runny nose
    3%
  • Vision abnormalities
    3%
  • Arthritis
    3%
  • Paranoid reaction
    2%
  • Urinary incontinence
    2%
  • Lung infection
    2%
  • Twitching
    2%
  • Swelling of joints
    2%
  • Peripheral swelling
    2%
  • Skin disorders
    2%
See more detailed side effects
11possible side effects
  • Skin irritation at the patch
    24%
  • Headache
    18%
  • Insomnia
    12%
  • Diarrhea
    9%
  • Dry mouth
    8%
  • Weight loss of at least 5%
    5%
  • Indigestion
    4%
  • Rash
    4%
  • Sore throat
    3%
  • Sinus infection
    3%
  • Weight gain of at least 5%
    2%
See more detailed side effects
Risks and risk factors
  • Impulse control problems
  • Problems with concentration
    • Taking with alcohol
    • Taking other medicines that make you sleepy
    • Sleep disorders
  • Low blood pressure
    • Taking blood pressure medicines
  • Kidney problems
    • Kidney problems
  • Skin cancer
    • Parkinson's disease
  • Hallucinations and behavior changes
    • Age 65 years or older
    • History of psychosis
    • Advanced Parkinson's disease
See more detailed risks and warnings
  • Increased blood pressure
    • Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats
    • Taking cough and cold medicines like dextromethorphan (Robitussin DM), pseudoephedrine (Sudafed)
  • Serotonin syndrome
    • Tricyclic antidepressants
    • Fentanyl
    • Tramadol
    • Buspirone
    • ADHD medicines
    • Triptans
  • Increased risk of skin cancer
  • Falling asleep during the day
    • Taking other medicines for Parkinson's
  • Low blood pressure
See more detailed risks and warnings