Compare Mirapex vs. Eldepryl
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Helps with movement problems.
Mirapex (pramipexole) is effective for Parkinson's disease or restless legs syndrome, but can cause extreme drowsiness that affects daily living.
Treats Parkinson's disease.
Used with other medicines for Parkinson's disease to boost its effect.
Upsides
- Mirapex (pramipexole) may be better for older people with Parkinson's since it causes fewer movement and mental changes than its alternatives.
- Mirapex (pramipexole) comes in extended-release form to help reduce side effects and ease administration.
- Available as a generic so it will be cheaper than similar brand medications.
- There are two different versions of Eldepryl (selegiline), a quick dissolving tablet and a regular tablet.
- Eldepryl (selegiline) is one of the recommended medicines you can take along with carbidopa/levodopa if your Parkinson's disease is getting worse.
Downsides
- Mirapex (pramipexole) can be used by itself, but is usually used in combination with other medications to treat Parkinson's.
- Not the best choice if you have kidney problems.
- You cannot suddenly stop taking Mirapex (pramipexole) if you have been taking it for a long time.
- You may have to limit the amount of cheese, smoked meat, and soy sauce you eat while taking Eldepryl (selegiline) since it can raise your blood pressure.
- Can keep you up at night if you take it later in the day
- Doesn't work by itself to treat Parkinson's disease.
Used for
- Parkinson's disease
- Restless legs syndrome
- Bipolar depression
Dosage forms
- Pill
- Extended release
- Pill
- Dissolving tablet
Price
Lowest price
$125.19
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$8238.23
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Side effects
36possible side effects
- Postural hypotension53%
- Muscle rigidity47%
- Extrapyramidal syndrome28%
- Insomnia27%
- Dizziness26%
- Hallucinations17%
- Accidental injury17%
- Dream abnormalities11%
- Confusion10%
- Muscle weakness10%
- Constipation10%
- Sleepiness9%
- Muscle problems8%
- Gait abnormalities7%
- Muscle tenseness7%
- Dry mouth7%
- Memory loss6%
- Urinary frequency6%
- General swelling4%
- Urinary tract infection4%
- Shortness of breath4%
- Accomodation abnormalities4%
- Restlessness3%
- Thinking abnormalities3%
- Chest pain3%
- Malaise3%
- Runny nose3%
- Vision abnormalities3%
- Arthritis3%
- Paranoid reaction2%
- Urinary incontinence2%
- Lung infection2%
- Twitching2%
- Swelling of joints2%
- Peripheral swelling2%
- Skin disorders2%
11possible side effects
- Skin irritation at the patch24%
- Headache18%
- Insomnia12%
- Diarrhea9%
- Dry mouth8%
- Weight loss of at least 5%5%
- Indigestion4%
- Rash4%
- Sore throat3%
- Sinus infection3%
- Weight gain of at least 5%2%
Risks and risk factors
- Impulse control problems
- Problems with concentration
- Taking with alcohol
- Taking other medicines that make you sleepy
- Sleep disorders
- Low blood pressure
- Taking blood pressure medicines
- Kidney problems
- Kidney problems
- Skin cancer
- Parkinson's disease
- Hallucinations and behavior changes
- Age 65 years or older
- History of psychosis
- Advanced Parkinson's disease
- Increased blood pressure
- Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats
- Taking cough and cold medicines like dextromethorphan (Robitussin DM), pseudoephedrine (Sudafed)
- Serotonin syndrome
- Tricyclic antidepressants
- Fentanyl
- Tramadol
- Buspirone
- ADHD medicines
- Triptans
- Increased risk of skin cancer
- Falling asleep during the day
- Taking other medicines for Parkinson's
- Low blood pressure