Compare Mirapex vs. Neupro

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Mirapex (pramipexole)

Prescription only

Neupro (rotigotine)

Prescription only
Helps with movement problems.

Mirapex (pramipexole) is effective for Parkinson's disease or restless legs syndrome, but can cause extreme drowsiness that affects daily living.

Helps with movement disorders due to Parkinson's or restless legs syndrome.

Neupro (rotigotine) is an effective treatment for Parkinson's disease or restless legs syndrome, but can cause troublesome side-effects related to impulse control.

Upsides
  • Mirapex (pramipexole) may be better for older people with Parkinson's since it causes fewer movement and mental changes than its alternatives.
  • Mirapex (pramipexole) comes in extended-release form to help reduce side effects and ease administration.
  • Available as a generic so it will be cheaper than similar brand medications.
  • Can use regardless of any pre-existing kidney or liver problems.
  • Single, daily patch provides all-day control of movement disorders.
  • Good alternative for those with difficulty swalloing pills.
  • Good option for elderly because of its lower risk for confusion or mental disturbances compared to other medicines like it.
Downsides
  • Mirapex (pramipexole) can be used by itself, but is usually used in combination with other medications to treat Parkinson's.
  • Not the best choice if you have kidney problems.
  • You cannot suddenly stop taking Mirapex (pramipexole) if you have been taking it for a long time.
  • Available as brand product only and may be expensive if not covered by your insurance.
  • Patch's adhesive may irritate the skin at site of application.
  • Heat exposure can affect stability of the patch.
  • Neupro (rotigotine) can lead to withdrawal symptoms if the medication is stopped suddenly.
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Used for
Dosage forms
  • Pill
  • Extended release
  • Patch
Price
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Reviews
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Side effects
36possible side effects
  • Postural hypotension
    53%
  • Muscle rigidity
    47%
  • Extrapyramidal syndrome
    28%
  • Insomnia
    27%
  • Dizziness
    26%
  • Hallucinations
    17%
  • Accidental injury
    17%
  • Dream abnormalities
    11%
  • Confusion
    10%
  • Muscle weakness
    10%
  • Constipation
    10%
  • Sleepiness
    9%
  • Muscle problems
    8%
  • Gait abnormalities
    7%
  • Muscle tenseness
    7%
  • Dry mouth
    7%
  • Memory loss
    6%
  • Urinary frequency
    6%
  • General swelling
    4%
  • Urinary tract infection
    4%
  • Shortness of breath
    4%
  • Accomodation abnormalities
    4%
  • Restlessness
    3%
  • Thinking abnormalities
    3%
  • Chest pain
    3%
  • Malaise
    3%
  • Runny nose
    3%
  • Vision abnormalities
    3%
  • Arthritis
    3%
  • Paranoid reaction
    2%
  • Urinary incontinence
    2%
  • Lung infection
    2%
  • Twitching
    2%
  • Swelling of joints
    2%
  • Peripheral swelling
    2%
  • Skin disorders
    2%
See more detailed side effects
22possible side effects
  • Nausea
    48%
  • Skin irritation
    32%
  • Dizziness
    22%
  • Vomiting
    20%
  • Sleepiness
    19%
  • Insomnia
    14%
  • Increased sweating
    11%
  • Anorexia
    9%
  • Fatigue
    6%
  • Visual disturbances
    5%
  • Constipation
    5%
  • Redness
    5%
  • Abnormal dreams
    3%
  • Abnormal electrocardiogram reading
    3%
  • Difficulty with maintaining balance
    3%
  • Upset stomach
    3%
  • Ringing in the ears
    3%
  • Hallucinations
    3%
  • Muscle spasms
    3%
  • Numbness of the hands and feet
    3%
  • Swelling of the hands and feet
    3%
  • White blood cells in urine
    3%
See more detailed side effects
Risks and risk factors
  • Impulse control problems
  • Problems with concentration
    • Taking with alcohol
    • Taking other medicines that make you sleepy
    • Sleep disorders
  • Low blood pressure
    • Taking blood pressure medicines
  • Kidney problems
    • Kidney problems
  • Skin cancer
    • Parkinson's disease
  • Hallucinations and behavior changes
    • Age 65 years or older
    • History of psychosis
    • Advanced Parkinson's disease
See more detailed risks and warnings
  • Sulfite sensitivity
  • Driving impairment
    • Taking other medicines that make you sleepy
    • Sleep disorders
  • Hallucinations and unusual changes in thought
    • Psychotic disorders
  • Low blood pressure
    • Taking blood pressure medicines
  • Impulse control problems
  • Heat exposure
See more detailed risks and warnings