Compare Morphine Sulfate vs. Percocet
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats severe pain.
Ms Contin (Morphine Sulfate) provides good long-term pain control without the need to take medicine frequently, but watch out for constipation.
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3.5/ 5 average rating with 541 reviewsforMorphine Sulfate
Treats moderate to severe pain.
Percocet (Oxycodone / Acetaminophen) is the strongest prescription combination pain medicine for as needed pain relief, but make sure you don't take too much acetaminophen (Tylenol) to avoid liver problems or death.
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3.8/ 5 average rating with 1399 reviewsforPercocet
Upsides
- Provides longer relieve for moderate to severe pain to improve quality of life.
- Good for chronic pain that requires around-the-clock relief.
- Might have fewer side effects than other opioid pain relievers.
- Combination pain medicine with an opioid component (oxycodone) and non-opioid component (acetaminophen or Tylenol) that takes advantage of different modes of pain relieve in a single pill.
- Provides quick relief for moderate to severe pain to improve quality of life.
- Generally considered stronger than Norco or other combination pain medicine for treating pain.
- Good for as-needed, short-term use, but may be helpful to manage more long-term pain problems if used at the appropriate doses and intervals.
- Lower rates of misuse compared to pure opioid medicines.
- Can help you fall asleep easier.
Downsides
- Doesn't work for as-needed or quick pain relief.
- Dizziness and drowsiness is common, but your body may adjust.
- Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Ms Contin (Morphine Sulfate) if you need.
- Long term use will likely cause physical dependence.
- Must be weaned slowly off the medicine after use longer than 2 weeks.
- Dizziness and drowsiness is common, but your body may adjust.
- Everyone will get constipation - always stay hydrated and take stool softener or stimulant on days you're taking Percocet if you need.
- All opioid containing medicines have the risk of physical dependence and possibility of withdrawal when used long-term.
- The non-opioid part of Percocet, acetaminophen (Tylenol), has a high risk of liver failure and death if you take more than the maximum daily dose. Be very careful.
- Relies on the users to be aware of how much acetaminophen (Tylenol) they are using since it is a very common ingredient in many prescription and non-prescription pain medicines.
- Avoid alcohol.
Used for
Dosage forms
- Pill
- Extended release
- Oral solution
- Liquid
- Suppository
- Pill
- Oral solution
Price
Lowest price
$136.12
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$132.34
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Reviews
541 reviews so far
55%
saidit'sworth it
43%
saiditworked well
20%
saidit'sa big hassle
Have you used Ms Contin (Morphine Sulfate)?
Leave a review1399 reviews so far
70%
saidit'sworth it
49%
saiditworked well
15%
saidit'sa big hassle
Have you used Percocet (Oxycodone / Acetaminophen)?
Leave a reviewSide effects
The Ms Contin (Morphine Sulfate) FDA package insert doesn’t have numbers about how common side effects are.
The Percocet (Oxycodone / Acetaminophen) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Death from lack of oxygen to the body (respiratory depression)
- Current use of medicine that affects liver enzyme CYP 3A4
- Age 65 or greater
- Higher dose
- People with not enough thyroid hormones
- History of lung problems
- Death from overdose
- Children age 18 and younger
- Death in newborn babies from opioid withdrawal (Neonatal opioid withdrawal syndrome)
- Long-term use during pregnancy
- Tolerance, dependence, and addiction
- Taking more than the prescribed dose
- Long-term use
- History of drug abuse
- Driving impairment
- Taking with alcohol
- Taking other medicines that make you less alert
- Age 65 or greater
- Low blood pressure
- Age 65 years or older
- Death from liver failure
- Current liver disease
- Taking with alcohol
- Taking other medicines with acetaminophen
- Death from lack of oxygen to the body (respiratory depression)
- Age 65 or greater
- Higher dose
- People with not enough thyroid hormones
- History of lung problems
- Driving impairment
- Taking with alcohol
- Taking other medicines that make you less alert
- Age 65 or greater
- Tolerance and dependence
- Taking more than the prescribed dose
- Long-term use
- History of drug abuse
- Neonatal withdrawal syndrome
- Long-term use of opioids in mother
- Breastfeeding while taking Percocet (Oxycodone / Acetaminophen)
- Death from overdose (extended-release tablet)
- Children age 18 and younger
- Taking more than prescribed dose
- Mixing with alcohol or drugs that interact with Percocet (Oxycodone / Acetaminophen)
- Severe allergic reactions
- Low blood pressure
- Age 65 years or older
- Circulation problems