Compare Movantik vs. Colace
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Movantik (naloxegol) is a good option for treating constipation due to the use of opioids. However, it can cause side effects that make you feel like you are going through opioid withdrawal.
Colace (docusate) softens the stool, but may not stimulate a bowel movement as quickly as a laxative.
- Is a good option if traditional laxatives have not worked for you.
- Take Movantik (naloxegol) only once a day.
- Compared to alternatives, this medicine doesn't affect your heart.
- Safer than laxatives.
- Available over-the-counter.
- Safe to use in children as young as 2 years old.
- Side effects of Movantik (naloxegol), including withdrawal and loss of pain control, may be worse in people taking certain opiates, such as methadone.
- More expensive than traditional laxatives. There is no generic available.
- Need to take this medicine on an empty stomach or it won't work as well.
- You may have to take a lower dose of Movantik (naloxegol) if you have kidney problems, which may be less effective or cause more side effects.
- May take up to 5 days for the full effects to kick in.
- Intended to be used only as a short-term solution for occasional constipation. Other options such as fiber supplements may be more useful for maintaining regular bowel movements.
- Opioid induced constipation
- Abdominal pain21%
- Excess sweating3%
- Opioid withdrawal & reduced pain relief
- Methadone use
- Severe abdominal pain and/or diarrhea
- Movantik 25mg
- Stomach or intestinal holes
- Crohns disease
- Peptic ulcer disease
- Diverticular disease
- Stomach malignancies
- Complete or partial blockage of intestines