Compare Movantik vs. Dulcolax

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Movantik (naloxegol)

Prescription only

Dulcolax (Bisacodyl)

Over-the-counter
Relieves constipation caused by opioid pain relievers.

Movantik (naloxegol) is a good option for treating constipation due to the use of opioids. However, it can cause side effects that make you feel like you are going through opioid withdrawal.

Treats constipation.

Dulcolax (Bisacodyl) works fast and the suppositories work even faster to relieve your constipation, as long as you're okay with it "cramping" your style a bit.

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3.8/ 5 average rating with 160 reviewsforDulcolax
Upsides
  • Is a good option if traditional laxatives have not worked for you.
  • Take Movantik (naloxegol) only once a day.
  • Compared to alternatives, this medicine doesn't affect your heart.
  • Most people said it was worth taking and it wasn't too much of a hassle.
  • Tablets give overnight relief of your constipation.
  • Dulcolax can also be used to treat constipation caused by spinal cord injury.
  • Suppositories give you quick relief without having to drink a large amount of liquid medicine.
Downsides
  • Side effects of Movantik (naloxegol), including withdrawal and loss of pain control, may be worse in people taking certain opiates, such as methadone.
  • More expensive than traditional laxatives. There is no generic available.
  • Need to take this medicine on an empty stomach or it won't work as well.
  • You may have to take a lower dose of Movantik (naloxegol) if you have kidney problems, which may be less effective or cause more side effects.
  • Dulcolax can cause cramping, stomach upset, feeling faint, and the feeling that you "have to go right now".
  • You have to be comfortable with putting the medicine in your rectum.
  • Suppositories can cause slight rectal burning.
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Used for
  • Opioid induced constipation
Dosage forms
  • Pill
  • Pill
  • Suppository
Price
Lowest price
$360.23
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Lowest price
$1.26
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Reviews
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160 reviews so far
65%
saidit'sworth it
49%
saiditworked well
16%
saidit'sa big hassle

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Side effects
7possible side effects
  • Abdominal pain
    21%
  • Diarrhea
    9%
  • Nausea
    8%
  • Gas
    6%
  • Vomiting
    5%
  • Headache
    4%
  • Excess sweating
    3%
See more detailed side effects
The Dulcolax (Bisacodyl) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Opioid withdrawal & reduced pain relief
    • Methadone use
  • Severe abdominal pain and/or diarrhea
    • Movantik 25mg
  • Stomach or intestinal holes
    • Crohns disease
    • Peptic ulcer disease
    • Diverticular disease
    • Stomach malignancies
See more detailed risks and warnings
  • Bowel blockage
    • Age 60 or older
    • Malignancy
    • Other condition that causes blockage or narrowing of bowel
    • Taking medications that cause constipation
  • Laxative dependence
    • Age 60 or greater
    • Taking medications that cause constipation
    • People who can't walk or move well (immobility)
  • Risk to fetus
    • Women of childbearing age
See more detailed risks and warnings
Learn more about Movantik (naloxegol)
Learn more about Dulcolax (Bisacodyl)