Compare Movantik vs. Miralax

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Movantik (naloxegol)

Prescription only
Relieves constipation caused by opioid pain relievers.

Movantik (naloxegol) is a good option for treating constipation due to the use of opioids. However, it can cause side effects that make you feel like you are going through opioid withdrawal.

Helps get things moving.

Miralax (Polyethylene Glycol) provides effective relief of constipation without "cramping" your style.

4.0/ 5 average rating with 226 reviewsforMiralax
Upsides
  • Is a good option if traditional laxatives have not worked for you.
  • Take Movantik (naloxegol) only once a day.
  • Compared to alternatives, this medicine doesn't affect your heart.
  • Miralax is the most recommended laxative by pharmacists and doctors.
  • Most people felt it was worth the hassle.
  • It's gluten and sugar free.
  • It causes little to no cramping, bloating, gas, or feelings like you "have to go right now" compared to some other medicines to treat constipation.
  • Works differently than other over-the-counter laxatives so it's a great alternative if other medicines haven't worked.
Downsides
  • Side effects of Movantik (naloxegol), including withdrawal and loss of pain control, may be worse in people taking certain opiates, such as methadone.
  • More expensive than traditional laxatives. There is no generic available.
  • Need to take this medicine on an empty stomach or it won't work as well.
  • You may have to take a lower dose of Movantik (naloxegol) if you have kidney problems, which may be less effective or cause more side effects.
  • You have to dissolve Miralax in a beverage and drink it versus taking a pill.
  • It's not for children 16 years or younger.
  • Miralax doesn't work overnight. It can take up to 2-4 days to have a bowel movement.
  • It's not recommended that you take it for more than a week, so it you haven't had any success, you'll need to call your doctor for other laxative options.
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Used for
Dosage forms
  • Pill
  • Liquid
Price
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Reviews
Not enough review data.Leave a review
226 reviews so far
75%
saidit'sworth it
54%
saiditworked well
10%
saidit'sa big hassle

Have you used Miralax (Polyethylene Glycol)?

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Side effects
7possible side effects
  • Abdominal pain
    21%
  • Diarrhea
    9%
  • Nausea
    8%
  • Gas
    6%
  • Vomiting
    5%
  • Headache
    4%
  • Excess sweating
    3%
See more detailed side effects
The Miralax (Polyethylene Glycol) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Opioid withdrawal & reduced pain relief
    • Methadone use
  • Severe abdominal pain and/or diarrhea
    • Movantik 25mg
  • Stomach or intestinal holes
    • Crohns disease
    • Peptic ulcer disease
    • Diverticular disease
    • Stomach malignancies
See more detailed risks and warnings
  • Electrolyte imbalance
    • Taking with medications that cause electrolyte imbalance
    • Age 60 or older
  • Risk to fetus
    • Women of childbearing age
  • Bowel blockage
    • Age 60 or older
    • Malignancy
    • Other condition that causes blockage or narrowing of bowel
    • Taking medications that cause constipation
See more detailed risks and warnings