Compare Mucinex DM vs. Codeine Guaifenesin

Head-to-head comparisons of medication uses, side effects, ratings, and more.

Breaks up mucus and relieves cough.

Mucinex Dm (Dextromethorphan / Guaifenesin) is okay for loosening congestion in your chest and throat, but it could prevent you from coughing the mucus up. It comes as an extended-release tablet and a short-acting liquid.

3.9/ 5 average rating with 15 reviewsforMucinex DM
No information currently available
  • Mucinex Dm (Dextromethorphan / Guaifenesin) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have chest congestion and a cough.
  • Helps loosen the mucus and phlegm that builds up in productive and wet coughs.
  • The extended release version of Mucinex DM lasts up to 12 hours.
No information currently available
  • Mucinex Dm (Dextromethorphan / Guaifenesin) isn’t useful if you have a dry cough without mucus or phlegm.
  • The two medications in this product could potentially work against each other. Guaifenesin makes mucus easier to cough up, while dextromethorphan (the "DM" in Mucinex Dm (Dextromethorphan / Guaifenesin)) stops you from coughing.
  • Can cause sleepiness, dizziness, and an upset stomach.
No information currently available
Used for
  • Cough
  • Due to minor throat and bronchial irritation
Dosage forms
  • Pill
  • Extended release
  • Liquid
  • Liquid
No pricing information available
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15 reviews so far
saidit'sworth it
saiditworked well
saidit'sa big hassle

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Side effects
The Mucinex Dm (Dextromethorphan / Guaifenesin) FDA package insert doesn’t have numbers about how common side effects are.
The Cheratussin Ac (Codeine / Guaifenesin) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Nausea and vomiting
  • Serotonin syndrome
    • Using other medications that affect serotonin
  • Cough warning
See more detailed risks and warnings
No information currently available