Compare Myfortic vs. Prograf

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Prograf (tacrolimus)

Prescription only
Prevents rejection of a transplanted organ.

Myfortic (mycophenolic acid) is good at preventing organ transplant rejection, but you’ll need regular blood tests.

Prevents rejection of a transplanted organ.

Prograf (tacrolimus) is a good medicine that prevents rejection of an organ transplant, but you will need to be on it lifelong.

Upsides
  • Myfortic (mycophenolic acid) is a first-choice medicine for preventing organ rejection since it lowers the risk of rejection and doesn't hurt the kidneys or liver like other medicines in its class.
  • By taking Myfortic (mycophenolic acid), your doctor might be able to lower the dose of your other anti-rejection medicines that have more side effects.
  • Causes less diarrhea, nausea, and vomiting compared to CellCept.
  • Prevents your body from rejecting a transplanted organ.
  • Available as an extended-release pill, so it can be taken just once daily.
  • Less cosmetic side-effects than other anti-rejection medicine like cyclosporine.
Downsides
  • You'll need regular blood tests, especially in the beginning, to make sure Myfortic (mycophenolic acid) isn't affecting your body in a bad way.
  • You might need to take other medicines to control your blood pressure, blood sugar, or cholesterol while on Myfortic (mycophenolic acid).
  • Regular blood tests are required for monitoring while on Prograf (tacrolimus).
  • Can cause a lot of side-effects, such as high blood sugar, high blood pressure, mental status changes, and kidney damage, especially with lifelong use.
  • Increases your risk of infection and certain cancers.
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Used for
  • Prevention of kidney transplant rejection
  • Psoriasis
  • Prevention of heart transplant rejection
  • Prevention of liver transplant rejection
  • Prevention of kidney transplant rejection
  • Lung transplant rejection
  • Bowel transplant rejection
  • Graft-versus-host disease
Dosage forms
  • Extended-release pill
  • Pill
  • Extended release
  • Injection
Price
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Reviews
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Side effects
25possible side effects
  • Constipation
    38%
  • Nausea
    28%
  • Urinary tract infection
    28%
  • Diarrhea
    24%
  • Trouble sleeping
    24%
  • Vomiting
    23%
  • Upset stomach
    23%
  • Low red blood cells
    22%
  • Cytomegalovirus (CMV) infection
    20%
  • Low white blood cells
    19%
  • High blood pressure
    18%
  • Swelling
    17%
  • High blood creatinine (marker of poorer kidney function)
    15%
  • Pain in upper part of stomach
    14%
  • Fever
    13%
  • High blood uric acid
    13%
  • Low blood potassium
    13%
  • Headache
    13%
  • High blood lipids (fats)
    12%
  • Back pain
    12%
  • Tremor
    12%
  • Low blood calcium
    11%
  • Low blood phosphorus
    11%
  • Gas
    10%
  • Joint pain
    7%
See more detailed side effects
13possible side effects
  • High blood pressure
    62%
  • Kidney Function Abnormal
    56%
  • Anemia
    50%
  • Low white blood cells
    48%
  • Viral infection
    32%
  • Diabetes Mellitus
    26%
  • Infection
    24%
  • High blood sugar
    23%
  • High cholesterol
    18%
  • Bronchitis
    17%
  • Urinary Tract Infection
    16%
  • Fluid around the heart
    15%
  • Tremor
    15%
See more detailed side effects
Risks and risk factors
  • Harm to unborn baby
    • Sexually active women of childbearing age
  • Serious infections
    • Taking other immunosuppressants
    • Age 60 or older
    • Weak immune system
  • Blood disorders
  • Cancer
    • Taking Myfortic (mycophenolic acid) for a long time
    • Prolonged exposure to sunlight
    • UV light
See more detailed risks and warnings
  • Serious infections
    • Taking other immunosuppressant drugs
    • Age 60 or older
    • Weak immune system
  • Cancer
    • Taking Prograf (tacrolimus) for a long time
  • Heart problems
    • History of heart problems
    • Taking drugs that interact with Prograf (tacrolimus)
    • High Prograf (tacrolimus) blood levels
  • Kidney damage
    • Poor kidney function
    • Taking other drugs that can damage the kidneys
    • Taking drugs that interact with Prograf (tacrolimus)
  • Diabetes
    • African-American descent
    • Hispanic descent
  • Increased risk of death in female liver transplant patients taking extended-release Prograf (tacrolimus)
    • Females using Astagraf XL
    • Liver transplantation
See more detailed risks and warnings