Compare Myfortic vs. Rapamune

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Rapamune (sirolimus)

Prescription only
Prevents rejection of a transplanted organ.

Myfortic (mycophenolic acid) is good at preventing organ transplant rejection, but you’ll need regular blood tests.

Prevents rejection of a transplanted organ.

Rapamune (sirolimus) is a reliable medicine that prevents rejection of an organ transplant but requires consistent monitoring.

Upsides
  • Myfortic (mycophenolic acid) is a first-choice medicine for preventing organ rejection since it lowers the risk of rejection and doesn't hurt the kidneys or liver like other medicines in its class.
  • By taking Myfortic (mycophenolic acid), your doctor might be able to lower the dose of your other anti-rejection medicines that have more side effects.
  • Causes less diarrhea, nausea, and vomiting compared to CellCept.
  • Rapamune (sirolimus) is good at preventing organ rejection.
  • Causes less harm to the kidneys with long-term use than similar medicines.
  • Fewer effects on blood sugar and blood pressure compared to other immunosuppressants.
  • Conveniently taken once daily.
Downsides
  • You'll need regular blood tests, especially in the beginning, to make sure Myfortic (mycophenolic acid) isn't affecting your body in a bad way.
  • You might need to take other medicines to control your blood pressure, blood sugar, or cholesterol while on Myfortic (mycophenolic acid).
  • You’ll need regular blood tests while taking Rapamune (sirolimus), especially when you first start the medicine.
  • Can cause high lipids (fats like cholesterol and triglycerides), especially with lifelong use. You might need to take other medicines to control your lipids while on Rapamune (sirolimus).
  • Raises your risk of infection and certain cancers.
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Used for
  • Prevention of kidney transplant rejection
  • Psoriasis
  • Prevention of kidney transplant rejection
  • Lymphangioleiomyomatosis
Dosage forms
  • Extended-release pill
  • Pill
  • Liquid
Price
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Reviews
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Side effects
25possible side effects
  • Constipation
    38%
  • Nausea
    28%
  • Urinary tract infection
    28%
  • Diarrhea
    24%
  • Trouble sleeping
    24%
  • Vomiting
    23%
  • Upset stomach
    23%
  • Low red blood cells
    22%
  • Cytomegalovirus (CMV) infection
    20%
  • Low white blood cells
    19%
  • High blood pressure
    18%
  • Swelling
    17%
  • High blood creatinine (marker of poorer kidney function)
    15%
  • Pain in upper part of stomach
    14%
  • Fever
    13%
  • High blood uric acid
    13%
  • Low blood potassium
    13%
  • Headache
    13%
  • High blood lipids (fats)
    12%
  • Back pain
    12%
  • Tremor
    12%
  • Low blood calcium
    11%
  • Low blood phosphorus
    11%
  • Gas
    10%
  • Joint pain
    7%
See more detailed side effects
17possible side effects
  • Swelling in arms and legs
    54%
  • High triglycerides
    45%
  • High blood pressure
    45%
  • High cholesterol
    43%
  • Higher blood creatinine (marker of poorer kidney function)
    39%
  • Constipation
    36%
  • Headache
    34%
  • Stomach pain
    28%
  • Urinary tract infection
    26%
  • Diarrhea
    25%
  • Nausea
    25%
  • Joint pain
    25%
  • Fever
    23%
  • Low red blood cells
    23%
  • Acne
    22%
  • Low white blood cells
    14%
  • Rash
    10%
See more detailed side effects
Risks and risk factors
  • Harm to unborn baby
    • Sexually active women of childbearing age
  • Serious infections
    • Taking other immunosuppressants
    • Age 60 or older
    • Weak immune system
  • Blood disorders
  • Cancer
    • Taking Myfortic (mycophenolic acid) for a long time
    • Prolonged exposure to sunlight
    • UV light
See more detailed risks and warnings
  • Health problems in people with liver and lung transplants
  • Cancer
    • Taking Rapamune (sirolimus) for a long time
    • Long exposure to sunlight
    • UV light
  • Serious infections
    • Taking other immunosuppressants
    • Age 60 or older
    • Weak immune system
  • High blood lipids (cholesterol and triglycerides)
    • History of high cholesterol
    • History of high triglycerides
  • Drug interactions
    • Taking multiple medicines
See more detailed risks and warnings