Compare nefazodone vs. Oleptro
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats depression.
Serzone (nefazodone) is usually used with other medicines to treat depression, but it is more likely to cause liver damage.
Improves mood and helps you sleep.
Oleptro (Trazodone) works well as a sleep aid, but has more side effects when used at higher doses for treating depression.
●●●●●
3.6/ 5 average rating with 59 reviewsforOleptro
Upsides
- Serzone (nefazodone) is a good choice to take with other medicines for depression if they haven't worked by themselves.
- Serzone (nefazodone) is available in generic.
- Commonly used in lower doses to help treat sleep problems (insomnia).
- Safer sleep medication than others (benzodiazepines or Unisom) for people age 65 and older.
- Fewer sexual side effects than many other antidepressants.
- Has been used for sleep and depression for a long time. There's a lot of information available about how it works and how safe it is.
- Comes as a generic medication and is cheaper than many other sleep aides.
- Six out of ten people who use an antidepressant for the first time find that it works for them.
Downsides
- While Serzone (nefazodone) is available as a generic, it's not considered a first or second choice medicine for depression because it is more likely to cause liver damage than other similar medicines.
- Serzone (nefazodone) is usually taken 2 times a day; the first choice medicines are only taken 1 time a day.
- It can take up to 3 months before you notice the full effects of Serzone (nefazodone).
- Compared to other similar medicines, Serzone (nefazodone) has a lot of interactions with other drugs, so your doctor might have to adjust the doses of your other medicines.
- Not as effective as other medications for depression.
- More sedating than other antidepressants.
- Causes more side effects when used at higher doses for depression. Includes sleepiness, dizziness, upset stomach, and irregular heartbeat.
- Like most antidepressants, can cause higher risk of suicidal thoughts and behavior for people age 24 and younger.
- The first antidepressant you try doesn't always work or it can cause side effects you really don't like. You might need to try a few different medications until you find one that works for you.
Used for
Dosage forms
- Pill
- Pill
- Extended release
Price
Lowest price
$40.00
Find instant savings near youLowest price
$4.00
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
Not enough review data.Leave a review
59 reviews so far
73%
saidit'sworth it
49%
saiditworked well
24%
saidit'sa big hassle
Have you used Oleptro (Trazodone)?
Leave a reviewSide effects
42possible side effects
- Headache36%
- Dry mouth25%
- Sleepiness25%
- Nausea22%
- Dizziness17%
- Constipation14%
- Weakness11%
- Trouble sleeping11%
- Lightheadedness10%
- Indigestion9%
- Blurry vision9%
- Infection8%
- Diarrhea8%
- Confusion7%
- Blind spots in vision7%
- Sore throat6%
- Increased appetite5%
- Changes in blood pressure4%
- Memory problems4%
- Tingling or prickling sensation4%
- Flushing4%
- Flu3%
- Swelling in the arms and legs3%
- Abnormal dreams3%
- Decreased concentration3%
- Increased cough3%
- Chills2%
- Fever2%
- Low blood pressure2%
- Itching2%
- Skin rashes2%
- Nausea and vomiting2%
- Trouble controlling movements2%
- Coordination problems2%
- Slowing of movement or speech2%
- Tremor2%
- Ringing in the ears2%
- Changes in taste2%
- Frequent urination2%
- Urinary tract infection2%
- Problems emptying bladder2%
- Vaginal discharge, itching, and pain2%
29possible side effects
- Somnolence/Sedation46%
- Drowsiness41%
- Dry Mouth34%
- Headache33%
- Dizziness/Lightheadedness28%
- Dry mouth25%
- Dizziness25%
- Nausea21%
- Blurred Vision15%
- Fatigue15%
- Nausea/Vomiting13%
- Diarrhea9%
- Constipation8%
- Skin Condition/Edema7%
- Weight Loss6%
- Nasal/Sinus Congestion6%
- Abdominal/Gastric Disorder6%
- Syncope5%
- Musculoskeletal Aches/Pains5%
- Tremors5%
- Nightmares/Vivid Dreams5%
- Weight Gain5%
- Back pain5%
- Vision blurred5%
- Sexual dysfunction5%
- Hypotension4%
- Incoordination2%
- Ejaculation disorders2%
- Decreased libido2%
Risks and risk factors
- Higher risk of suicide
- People under age 24
- Liver failure
- Low blood pressure
- Taking medicine for high blood pressure
- Possible bipolar disorder
- Seizures
- History of seizures
- Lower heart rate
- History of heart attack or heart disease
- Medicines that slow the heartbeat
- Suicidal thoughts or behavior
- Age 24 years or younger
- Seizures
- History of seizures
- Alcoholism
- Eating disorder
- Higher dose
- Drug interactions
- Painful erection
- Low blood pressure
- Age 65 years or older
- Driving impairment
- Alcohol
- Taking other medicines that make you less alert