Compare Nesina vs. glyburide
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Nesina (alogliptin) is a good add-on treatment for diabetes if your blood sugars are still not controlled, but it doesn't work as well as insulin.
Diabeta (glyburide) is a good oral anti-diabetic medicine, but can cause hypoglycemia or low blood sugar.
- Less likely to cause weight gain or low blood sugar compared to other anti-diabetic medicines.
- Pill may be preferred by some patients over injection.
- Available as an oral tablet.
- Lowers your A1c (average blood sugar over time) up to 2%.
- Available in generic version.
- Available in single pill combination with other anti-diabetic medicines.
- Does not lower your A1c (average blood sugar over time) as much as insulin.
- Available as an expensive, branded product only.
- Has more troublesome side-effects than other anti-diabetic pills.
- More likely to cause hypoglycemia or low blood sugar than other types of oral anti-diabetics.
- You will have to check your blood sugar often when you first start taking it.
- Can cause weight gain (about 2 to 3 pounds).
- Not ideal for elderly or those with poor kidney function.
- May not work as well for those with severe diabetes and when pancreas cannot produce insulin.
- Nausea and heartburn2%
- Skin allergies2%
- Pancreatitis (inflammation of the pancreas)
- History of pancreatitis
- High blood triglyceride levels
- Gallstones (stones in gallbladder)
- Liver damage
- Serious allergic reactions
- Low blood sugar (hypoglycemia)
- Taking medicines for diabetes
- Severe joint pain and swelling
- Low blood sugar
- Over age 65
- Kidney problems
- Use of other blood sugar lowering medicines
- Intense physical activity
- Severe allergic reactions
- History of sulfa allergies