Compare Neupro vs. Azilect

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Neupro (rotigotine)

Prescription only

Azilect (rasagiline)

Prescription only
Helps with movement disorders due to Parkinson's or restless legs syndrome.

Neupro (rotigotine) is an effective treatment for Parkinson's disease or restless legs syndrome, but can cause troublesome side-effects related to impulse control.

Treats Parkinson's disease.

Azilect (rasagiline) is one of the recommended medicines to treat Parkinson's disease. It is now available in generic, which makes it more affordable for people without insurance.

Upsides
  • Can use regardless of any pre-existing kidney or liver problems.
  • Single, daily patch provides all-day control of movement disorders.
  • Good alternative for those with difficulty swalloing pills.
  • Good option for elderly because of its lower risk for confusion or mental disturbances compared to other medicines like it.
  • Azilect (rasagiline) is one of the go-to medicines for Parkinson's disease. It can be used in early and late stages of the disease.
  • Taking Azilect (rasagiline) by itself can help slow down Parkinson's disease, but it works better when it's given with other medicines.
  • Azilect (rasagiline) is available as generic as well as brand name, so there are usually lower out-of-pocket costs for you with insurance.
Downsides
  • Available as brand product only and may be expensive if not covered by your insurance.
  • Patch's adhesive may irritate the skin at site of application.
  • Heat exposure can affect stability of the patch.
  • Neupro (rotigotine) can lead to withdrawal symptoms if the medication is stopped suddenly.
  • It can cause unusual cravings and changes in behavior in some people.
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Used for
Dosage forms
  • Patch
  • Pill
Price
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Reviews
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Side effects
22possible side effects
  • Nausea
    48%
  • Skin irritation
    32%
  • Dizziness
    22%
  • Vomiting
    20%
  • Sleepiness
    19%
  • Insomnia
    14%
  • Increased sweating
    11%
  • Anorexia
    9%
  • Fatigue
    6%
  • Visual disturbances
    5%
  • Constipation
    5%
  • Redness
    5%
  • Abnormal dreams
    3%
  • Abnormal electrocardiogram reading
    3%
  • Difficulty with maintaining balance
    3%
  • Upset stomach
    3%
  • Ringing in the ears
    3%
  • Hallucinations
    3%
  • Muscle spasms
    3%
  • Numbness of the hands and feet
    3%
  • Swelling of the hands and feet
    3%
  • White blood cells in urine
    3%
See more detailed side effects
46possible side effects
  • Difficulty controlling movement
    18%
  • Headache
    14%
  • Accidental injury
    12%
  • Nausea
    12%
  • Falls
    11%
  • Weight loss
    9%
  • Constipation
    9%
  • Low blood pressure
    9%
  • Joint pain
    8%
  • Indigestion
    7%
  • Dizziness
    7%
  • Swelling in arms and legs
    7%
  • Vomiting
    7%
  • Dry mouth
    6%
  • Rash
    6%
  • Sleepiness
    6%
  • Depression
    5%
  • Flu-like symptoms
    5%
  • Abdominal pain
    5%
  • Loss of appetite
    5%
  • Diarrhea
    5%
  • Bruising
    5%
  • Tingling or prickling sensation
    5%
  • Back pain
    4%
  • Cough
    4%
  • Trouble sleeping
    4%
  • Cold or flu
    4%
  • Unusual dreams
    4%
  • Hallucinations
    4%
  • Eyelid problems
    3%
  • Fever
    3%
  • Stomach infection
    3%
  • Stuffy nose
    3%
  • Movement coordination problems
    3%
  • Shortness of breath
    3%
  • Infections
    3%
  • Neck pain
    3%
  • Sweating
    3%
  • Tendon swelling
    3%
  • Uncontrollable muscle movements
    3%
  • Arthritis
    2%
  • Weakness
    2%
  • Gum swelling
    2%
  • Excessive bleeding
    2%
  • Hernia
    2%
  • Muscle weakness
    2%
See more detailed side effects
Risks and risk factors
  • Sulfite sensitivity
  • Driving impairment
    • Taking other medicines that make you sleepy
    • Sleep disorders
  • Hallucinations and unusual changes in thought
    • Psychotic disorders
  • Low blood pressure
    • Taking blood pressure medicines
  • Impulse control problems
  • Heat exposure
See more detailed risks and warnings
  • Increased blood pressure
    • Eating foods rich in tyramine, like soy sauce, fermented cheese and smoked meats
  • Serotonin syndrome
    • Tricyclic antidepressants
    • Fentanyl
    • Tramadol
    • Buspirone
    • ADHD medicines
    • Triptans
    • dextromethorphan
    • pseudoephedrine
  • Falling asleep during the day
    • Taking other medicines for Parkinson's disease
  • Low blood pressure
  • Movement problems
    • Taking other medicines for Parkinson's disease
  • Lack of impulse control
    • Taking other medicines for Parkinson's disease
See more detailed risks and warnings