Compare Neupro vs. carbidopa / levodopa / entacapone
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Helps with movement disorders due to Parkinson's or restless legs syndrome.
Neupro (rotigotine) is an effective treatment for Parkinson's disease or restless legs syndrome, but can cause troublesome side-effects related to impulse control.
Treats Parkinson's disease.
Stalevo (carbidopa / levodopa / entacapone) is a good choice for Parkinson's disease, especially when carbidopa/levodopa starts losing its effect.
Upsides
- Can use regardless of any pre-existing kidney or liver problems.
- Single, daily patch provides all-day control of movement disorders.
- Good alternative for those with difficulty swalloing pills.
- Good option for elderly because of its lower risk for confusion or mental disturbances compared to other medicines like it.
- It combines three medicines into one pill so you don't have to take so many pills daily.
- Stalevo (carbidopa / levodopa / entacapone) is available as a generic.
Downsides
- Available as brand product only and may be expensive if not covered by your insurance.
- Patch's adhesive may irritate the skin at site of application.
- Heat exposure can affect stability of the patch.
- Neupro (rotigotine) can lead to withdrawal symptoms if the medication is stopped suddenly.
- You would first start by taking Stalevo (carbidopa / levodopa / entacapone) as two different pills, carbidopa/levodopa and entacapone, before you get switched over to Stalevo (carbidopa / levodopa / entacapone).
- It's less customizable since there are only a few fixed combinations available.
Used for
Dosage forms
- Patch
- Pill
Price
Lowest price
$674.16
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$97.90
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Side effects
22possible side effects
- Nausea48%
- Skin irritation32%
- Dizziness22%
- Vomiting20%
- Sleepiness19%
- Insomnia14%
- Increased sweating11%
- Anorexia9%
- Fatigue6%
- Visual disturbances5%
- Constipation5%
- Redness5%
- Abnormal dreams3%
- Abnormal electrocardiogram reading3%
- Difficulty with maintaining balance3%
- Upset stomach3%
- Ringing in the ears3%
- Hallucinations3%
- Muscle spasms3%
- Numbness of the hands and feet3%
- Swelling of the hands and feet3%
- White blood cells in urine3%
20possible side effects
- Difficulty controlling movements25%
- Muscle spasm10%
- Changes in urine color10%
- Discolored urine10%
- Muscle rigidity9%
- Dizziness8%
- Abdominal pain8%
- Fatigue6%
- Constipation6%
- Back pain5%
- Vomiting4%
- Dry mouth3%
- Shortness of breath3%
- Bruising3%
- Increased sweating2%
- Anxiety2%
- Sleepiness2%
- Indigestion2%
- Flatulence2%
- Weakness2%
Risks and risk factors
- Sulfite sensitivity
- Driving impairment
- Taking other medicines that make you sleepy
- Sleep disorders
- Hallucinations and unusual changes in thought
- Psychotic disorders
- Low blood pressure
- Taking blood pressure medicines
- Impulse control problems
- Heat exposure
- Difficulty controlling movements
- Diarrhea
- Muscle damage
- Changes in blood pressure and falls
- Stomach bleeding
- History of stomach ulcers