Compare Neurontin vs. Seroquel
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats tingling and burning nerve pain.
Neurontin (gabapentin) is an old seizure disorder medicine that is now used to treat nerve-related pain caused by different conditions.
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3.4/ 5 average rating with 620 reviewsforNeurontin
Helps control your thoughts and mood.
Seroquel (quetiapine) is a effective at treating schizophrenia, mania, and depression but it can cause weight gain and high blood glucose levels.
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3.7/ 5 average rating with 250 reviewsforSeroquel
Upsides
- Originally used to treat epilepsy (partial seizures), but now it primarily treats neuropathic pain that's caused by nerve stimulation or damage.
- Studies show it's most effective for nerve pain from diabetes, shingles, and fibromyalgia (a painful muscle condition).
- It's available as a generic, so it's less expensive than similar medications.
- Seroquel (quetiapine) is effective at relieving psychotic symptoms and manic episodes.
- Seroquel (quetiapine) has fewer side effects than most antipsychotic medications.
- Seroquel (quetiapine) is less likely to cause heart problems compared to some other antipsychotics.
- Seroquel (quetiapine) is also the least likely to cause Extrapyramidal Symptoms (EPS) – a movement disorder that causes stiffness, tremor, restlessness, and slow, repetitive, or involuntary movements.
Downsides
- Neurontin (gabapentin) can cause some side effects, including memory problems, drowsiness, dizziness, or confusion. There is a higher risk for these side effects if you drink alcohol, so it might not be the best medication for heavy drinkers.
- You can't skip or miss doses since suddenly stopping Neurontin (gabapentin) can cause seizures.
- Seroquel (quetiapine) has a moderate to high risk of weight gain, elevated cholesterol and/or blood sugar compared to other antipsychotics.
- You might need routine blood tests to check how Seroquel (quetiapine) is affecting your body.
Used for
Dosage forms
- Pill
- Oral solution
- Extended release
- Pill
- Extended release
Price
Lowest price
$597.21
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$12.95
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Reviews
620 reviews so far
57%
saidit'sworth it
40%
saiditworked well
19%
saidit'sa big hassle
Have you used Neurontin (gabapentin)?
Leave a review250 reviews so far
56%
saidit'sworth it
50%
saiditworked well
27%
saidit'sa big hassle
Have you used Seroquel (quetiapine)?
Leave a reviewSide effects
20possible side effects
- Dizziness28%
- Drowsiness21%
- Swelling in the limbs8%
- Abnormal physical weakness6%
- Diarrhea6%
- Infection5%
- Dry mouth5%
- Constipation4%
- Nausea4%
- Headache3%
- Accidental injury3%
- Stomach pain3%
- Vomiting3%
- Worse coordination3%
- Thinking abnormal3%
- Decreased vision3%
- Gas2%
- Weight gain2%
- Abnormal gait2%
- Lack of coordination2%
36possible side effects
- Drowsiness34%
- Dry mouth19%
- Headache17%
- Weakness10%
- Constipation10%
- Dizziness9%
- Tremor8%
- Stomach pain7%
- Low blood pressure7%
- Agitation6%
- Weight gain6%
- Sore throat6%
- Back pain5%
- Stiffness/difficulty moving4%
- Hay fever4%
- Swelling in the limbs4%
- Twitching4%
- Indigestion4%
- Depression3%
- Lazy eye3%
- Speech disorder3%
- Altered hormone levels3%
- Heaviness2%
- Infection2%
- Fever2%
- High blood pressure2%
- Increased heart rate2%
- Increased appetite2%
- Hypothyroidism2%
- Incoordination2%
- Abnormal thinking2%
- Anxiety2%
- Loss of control of movements2%
- Sinus infection2%
- Sweating2%
- Urinary Tract Infection2%
Risks and risk factors
- Suicidal thoughts or behavior
- Neurologic and psychiatric side effects (children)
- Children ages 3 to 12
- Serious allergic reaction and multiple organ problems
- Driving impairment
- Taking Neurontin (gabapentin) with alcohol
- Taking other medicines that cause dizziness and/or drowsiness
- Withdrawal seizures
- Stopping Neurontin (gabapentin) suddenly
- Higher risk of death
- Elderly patients with dementia-related psychosis
- Suicidal thoughts or behavior
- Children, adolescents, and young adults (<24 years old)
- Neuroleptic malignant syndrome
- Heart problems
- History of heart problems
- Drug interactions
- Extrapyramidal Symptoms (EPS)
- Metabolic changes (increased blood sugar, high cholesterol and weight gain)
- People with diabetes
- People with high cholesterol