Compare Nexium vs. Pepcid
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Nexium (esomeprazole) gives you long-lasting heartburn relief but has some risks if used long term.
Pepcid (Famotidine) works well for heartburn but may not last as long or start working as quickly as other antacids.
- Most people can take Nexium (esomeprazole) without any noticeable day-to-day side effects.
- Nexium (esomeprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once a day.
- You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need quicker relief.
- Nexium (esomeprazole) is inexpensive, with over-the-counter and generic options.
- Coupons are available for the brand name - speak to your doctor or pharmacist.
- The packet form is a good option if you have trouble swallowing pills.They can be mixed with water for easier swallowing.
- Most people can take Famotidine without any noticeable day-to-day side effects.
- Famotidine lasts longer than many other antacids like Maalox and Tums, and you only need to take it once or twice a day.
- You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
- Available as both a generic and over-the-counter option, so it's pretty affordable.
- Few drug interactions.
- Doesn't start working right away like antacids (Tums, Rolaids, or Maalox).
- It can take several days or weeks to start feeling benefits.
- May not be the best choice for patients 65 years of age and older due to risk of bone fractures and severe diarrhea.
- Other antacids like Maalox, Tums, or Rolaids often start to work more quickly than Famotidine.
- Medication like omeprazole (proton pump inhibitors) works better at healing and preventing stomach ulcers than medication like Famotidine (H2 blockers).
- Can cause more serious side effects for people with kidney disease. Ask your doctor to give you a lower dose or choose a different option.
- H. Pylori bacterial infection
- Prevention and treatment of NSAID-induced gastric ulcers
- Chewable tablet
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- Stomach cancer
- Kidney injury
- Severe diarrhea
- Being treated at a hospital
- Bone fractures
- High dose Nexium (esomeprazole)
- Long-term treatment with Nexium (esomeprazole)
- Low bone mineral density
- Aged 65 years or older
- Hiding possible cancer
- Increased side effects
- Current kidney disease
- Allergic reaction