Compare Niaspan vs. Lopid

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Niaspan (Niacin)

Prescription only

Lopid (gemfibrozil)

Prescription only
Lowers cholesterol.

Niaspan (Niacin) lowers triglycerides, but isn't as good as statins for improving cholesterol levels.

3.2/ 5 average rating with 380 reviewsforNiaspan
Lowers cholesterol and triglyceride levels.

Lopid (gemfibrozil) works well to lower triglycerides and bad cholesterol, but it may not be the best option if you're also on a statin drug.

Upsides
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good for lowering triglycerides (fats).
  • Lopid (gemfibrozil) is available as a generic.
  • It can significantly lower your triglycerides and bad cholesterol (LDL), and raise your good cholesterol (HDL).
  • More effective and causes fewer side effects than non-statin cholesterol-lowering medicines.
Downsides
  • By itself, Niaspan (Niacin) isn't as effective as statins for improving cholesterol levels.
  • It can cause flushing and stomach pain or discomfort.
  • You need to take it before bedtime with a low-fat snack.
  • If you miss doses often, you may need to re-start taking the medicine more regularly at a lower dose.
  • Since so many people use statin medications to treat their cholesterol, Lopid (gemfibrozil) isn't generally the first choice treatment to use since it can interact with statins.
  • Can be more expensive than some alternative medicines.
  • Need to take Lopid (gemfibrozil) twice a day, whereas other similar medications are only once a day.
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Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
Price
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Reviews
380 reviews so far
43%
saidit'sworth it
31%
saiditworked well
19%
saidit'sa big hassle

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Side effects
6possible side effects
  • Flushing
    68%
  • Itching
    8%
  • Diarrhea
    7%
  • Nausea
    5%
  • Rash
    5%
  • Cough increased
    3%
See more detailed side effects
9possible side effects
  • Stomach and intestinal problems
    34%
  • Stomach upset
    20%
  • Abdominal pain
    10%
  • Diarrhea
    7%
  • Fatigue
    4%
  • Nausea or vomiting
    3%
  • Eczema
    2%
  • Rash
    2%
  • Feeling off balance
    2%
See more detailed side effects
Risks and risk factors
  • Muscle pain
    • Taking Niaspan (Niacin) with statins
  • Liver damage
    • Heavy alcohol use
    • Past history of liver disease
  • High blood sugar
    • Diabetes
  • Low platelets
    • Taking Niaspan (Niacin) with anticoagulants
  • Gout
    • Gout
See more detailed risks and warnings
  • Muscle pain
    • Taking Lopid (gemfibrozil) with statins
  • Liver problems
    • Past history of liver disease
  • Kidney problems
    • Kidney problems
  • Bleeding risk
    • Taking Lopid (gemfibrozil) with anticoagulants
  • Breastfeeding
  • Gallstones
See more detailed risks and warnings