Compare Niaspan vs. Trilipix

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Niaspan (Niacin)

Prescription only

Trilipix (Fenofibric Acid)

Prescription only
Lowers cholesterol.

Niaspan (Niacin) lowers triglycerides, but isn't as good as statins for improving cholesterol levels.

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3.2/ 5 average rating with 380 reviewsforNiaspan
Lowers cholesterol.

Trilipix is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol and cardiovascular disease risk.

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2.9/ 5 average rating with 68 reviewsforTrilipix
Upsides
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good for lowering triglycerides (fats).
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good medicine for lowering triglycerides.
Downsides
  • By itself, Niaspan (Niacin) isn't as effective as statins for improving cholesterol levels.
  • It can cause flushing and stomach pain or discomfort.
  • You need to take it before bedtime with a low-fat snack.
  • If you miss doses often, you may need to re-start taking the medicine more regularly at a lower dose.
  • In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
  • Different forms and strengths of this medication can't be substituted for each other.
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Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Extended release
Price
Lowest price
$21.04
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Lowest price
$23.67
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Reviews
380 reviews so far
43%
saidit'sworth it
31%
saiditworked well
19%
saidit'sa big hassle

Have you used Niaspan (Niacin)?

Leave a review
68 reviews so far
50%
saidit'sworth it
22%
saiditworked well
25%
saidit'sa big hassle

Have you used Trilipix (Fenofibric Acid)?

Leave a review
Side effects
6possible side effects
  • Flushing
    68%
  • Itching
    8%
  • Diarrhea
    7%
  • Nausea
    5%
  • Rash
    5%
  • Cough increased
    3%
See more detailed side effects
The Trilipix (Fenofibric Acid) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Muscle pain
    • Taking Niaspan (Niacin) with statins
  • Liver damage
    • Heavy alcohol use
    • Past history of liver disease
  • High blood sugar
    • Diabetes
  • Low platelets
    • Taking Niaspan (Niacin) with anticoagulants
  • Gout
    • Gout
See more detailed risks and warnings
  • Muscle pain
    • Taking Trilipix (Fenofibric Acid) with statins
  • Liver damage
    • Past history of liver disease
  • Gallstones
  • Increased bleeding risk
    • Taking Trilipix (Fenofibric Acid) with anticoagulants
  • Pancreatitis
  • Changes in blood tests
  • Skin reactions
  • Blood clots
  • Increased risk for colds and flu
See more detailed risks and warnings
Learn more about Niaspan (Niacin)
Learn more about Trilipix (Fenofibric Acid)