Compare Niaspan vs. Trilipix

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT

Niaspan (Niacin)

Prescription only

Trilipix (Fenofibric Acid)

Prescription only
Lowers cholesterol.

Niaspan (Niacin) lowers triglycerides, but isn't as good as statins for improving cholesterol levels.

●●●●●
3.2/ 5 average rating with 380 reviewsforNiaspan
Lowers cholesterol.

Trilipix is good for lowering triglycerides (fats), but it's not as good as statins for improving cholesterol and cardiovascular disease risk.

●●●●●
2.9/ 5 average rating with 68 reviewsforTrilipix
Upsides
  • Lowers "bad" cholesterol (LDL) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good for lowering triglycerides (fats).
  • Lowers "bad" cholesterol (LDL) and triglycerides (fats) and raises "good" cholesterol (HDL) in people who have trouble doing this through diet and exercise.
  • Good medicine for lowering triglycerides.
Downsides
  • By itself, Niaspan (Niacin) isn't as effective as statins for improving cholesterol levels.
  • It can cause flushing and stomach pain or discomfort.
  • You need to take it before bedtime with a low-fat snack.
  • If you miss doses often, you may need to re-start taking the medicine more regularly at a lower dose.
  • In clinical studies, Trilipix hasn't lowered cholesterol or the risk of heart attack and stroke better than statins.
  • Different forms and strengths of this medication can't be substituted for each other.
ADVERTISEMENT
Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Extended release
Price
Lowest price
$25.90
Find instant savings near you
Lowest price
$14.00
Find instant savings near you
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
380 reviews so far
43%
saidit'sworth it
31%
saiditworked well
19%
saidit'sa big hassle

Have you used Niaspan (Niacin)?

Leave a review
68 reviews so far
50%
saidit'sworth it
22%
saiditworked well
25%
saidit'sa big hassle

Have you used Trilipix (Fenofibric Acid)?

Leave a review
Side effects
6possible side effects
  • Flushing
    68%
  • Itching
    8%
  • Diarrhea
    7%
  • Nausea
    5%
  • Rash
    5%
  • Cough increased
    3%
See more detailed side effects
The Trilipix (Fenofibric Acid) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Muscle pain
    • Taking Niaspan (Niacin) with statins
  • Liver damage
    • Heavy alcohol use
    • Past history of liver disease
  • High blood sugar
    • Diabetes
  • Low platelets
    • Taking Niaspan (Niacin) with anticoagulants
  • Gout
    • Gout
See more detailed risks and warnings
  • Muscle pain
    • Taking Trilipix (Fenofibric Acid) with statins
  • Liver damage
    • Past history of liver disease
  • Gallstones
  • Increased bleeding risk
    • Taking Trilipix (Fenofibric Acid) with anticoagulants
  • Pancreatitis
  • Changes in blood tests
  • Skin reactions
  • Blood clots
  • Increased risk for colds and flu
See more detailed risks and warnings
Learn more about Niaspan (Niacin)
Learn more about Trilipix (Fenofibric Acid)