Compare Nifedipine vs. Catapres

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Procardia (Nifedipine)

Prescription only

Catapres (Clonidine)

Prescription only
Lowers blood pressure and controls heart rate.

Nifedipine works well to lower blood pressure and prevent chest pain, but you have to be okay with avoiding grapefruit. You can't miss doses, and you might get persistent swelling.

2.8/ 5 average rating with 26 reviewsforNifedipine
Lowers blood pressure.

Catapres (Clonidine) is a good addition if you need more than one medicine to control your blood pressure, but it has a lot of side effects. You can't miss doses.

3.2/ 5 average rating with 78 reviewsforCatapres
Upsides
  • A first-choice blood pressure treatment for many people.
  • Calcium channel blockers work especially well for African Americans to lower blood pressure.
  • You can take it alone or with other medicines to help lower blood pressure.
  • Lowers the risk of heart attack and stroke.
  • Prevents heart-related chest pain (angina) if you take it regularly.
  • Treats certain abnormal heart rhythms.
  • Can be added to other blood pressure-lowering medicines if you need additional blood pressure control.
  • Available in a weekly patch for people that aren't good at taking medicine by mouth.
  • Works in the brain, so it can help treat some nervous system and psychiatric conditions.
  • Under the brand name Kapvay, it's used to treat ADHD in children and teenagers.
Downsides
  • Calcium channel blockers can cause swelling in your limbs. If this happens for you, it probably won't get better over time, so talk to your doctor about alternatives if it bothers you.
  • Women are more likely to have side effects (especially swelling) from Nifedipine than men.
  • You can't miss doses. Stopping Nifedipine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
  • Not a good medication for you if you love grapefruit. It can make Nifedipine have a stronger effect on your blood pressure.
  • Has a lot of side effects compared to other blood pressure-lowering medicine because it works in the brain.
  • The pill form can make some people sleepy, dizzy, and have dry mouth.
  • You can't miss doses. Stopping Clonidine suddenly can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke.
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Used for
Dosage forms
  • Pill
  • Extended release
  • Pill
  • Extended release
  • Patch
Price
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Reviews
26 reviews so far
42%
saidit'sworth it
31%
saiditworked well
46%
saidit'sa big hassle

Have you used Procardia (Nifedipine)?

Leave a review
78 reviews so far
42%
saidit'sworth it
33%
saiditworked well
35%
saidit'sa big hassle

Have you used Catapres (Clonidine)?

Leave a review
Side effects
11possible side effects
  • Dizziness, lightheadedness, giddiness
    27%
  • Flushing
    25%
  • Headache
    23%
  • Weakness
    12%
  • Nausea, heartburn
    11%
  • Muscle cramps, tremor
    8%
  • Peripheral edema
    7%
  • Nervousness, mood changes
    7%
  • Palpitation
    7%
  • Dyspnea, cough, wheezing
    6%
  • Nasal congestion, sore throat
    6%
See more detailed side effects
17possible side effects
  • Erythema / pruritis
    26%
  • Dry mouth
    25%
  • Drowsiness
    12%
  • Localized vesiculation
    7%
  • Fatigue
    6%
  • Headache
    5%
  • Allergic contact sensitization
    5%
  • Hyperpigmentation
    5%
  • Lethargy
    3%
  • Sedation
    3%
  • Edema
    3%
  • Excoriation
    3%
  • Burning
    3%
  • Insomnia
    2%
  • Dizziness
    2%
  • Impotence/sexual dysfunction
    2%
  • Dry throat
    2%
See more detailed side effects
Risks and risk factors
  • Intestinal blockage
    • Taking anti-inflammatories, acid reducers in the stomach, anticholinergics, laxatives, levothyroxine
    • History of intestinal surgery
  • Chest pain
    • Taking beta-blockers
    • Severe coronary artery disease.
  • Liver damage/jaundice
    • History of cirrhosis
  • Low blood pressure
  • Congestive heart failure
    • History of tight aortic stenosis
    • Taking beta-blockers
  • Heart attack or increased chest pain
    • Obstructive coronary artery disease
See more detailed risks and warnings
  • Withdrawal
    • Sudden discontinuation of medicine
  • Driving impairment
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Low heart rate (bradycardia)
    • Age 65 years or older
    • Using other medicine(s) that slows the heart
See more detailed risks and warnings