Compare Novolog vs. Levemir

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Novolog (insulin aspart)

Prescription only

Levemir (insulin detemir)

Prescription only
Lowers blood sugar.

Novolog (insulin aspart) is a fast-acting insulin that provides meal-time blood sugar control. For long-term control, you'll need to take Novolog (insulin aspart) with other medicines to keep your overall blood sugar down.

3.5/ 5 average rating with 177 reviewsforNovolog
Lowers blood sugar.

Levemir (insulin detemir) is an effective, long-acting insulin that provides all-day sugar control, but there are similar medications that can be used instead.

3.3/ 5 average rating with 130 reviewsforLevemir
Upsides
  • When used correctly, this medication will l lower blood sugar every time you use it and prevent the harmful, long-term effects of high sugar levels on your organs and blood vessels.
  • You can easily change the dose of Novolog (insulin aspart) to fit your individual needs.
  • Starting insulin early in the treatment of Type 2 diabetes can maintain your body's insulin-producing cells and slow down disease progression.
  • Can use Novolog (insulin aspart) even if you have liver or kidney problems, unlike many other blood sugar-lowering medicines.
  • Insulin is the most effective blood sugar lowering medication, as it lowers A1c (average blood sugar over time) up to 2 or 3%. When used correctly, it'll prevent the harmful effects of high blood sugar levels on your organs and blood vessels.
  • Levemir (insulin detemir) is a long lasting insulin that provides consistent, all-day blood sugar control with less risk of low blood sugar.
  • Doses can be easily adjusted to make a customized regimen that's tailored to your body's needs.
  • Starting insulin early in the treatment of type 2 diabetes can maintain your body's insulin producing cells and slow down disease progression.
  • Levemir (insulin detemir) can be used in people with liver or kidney problems.
Downsides
  • Have to take insulin by injection.
  • Might have to check your blood sugar multiple times a day, usually before each meal.
  • Novolog (insulin aspart) is likely to cause moderate weight gain.
  • Higher risk of low blood sugar episodes compared to other kinds of diabetes medications.
  • You have to take Levemir (insulin detemir) by injection.
  • You have to check your blood sugar regularly.
  • There is a risk of low blood sugar episodes with use of Levemir (insulin detemir).
  • Levemir (insulin detemir) can cause tiredness, moderate weight gain, and swelling in your hands, ankles, or feet.
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Used for
Dosage forms
  • Injection
  • Injection
Price
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Reviews
177 reviews so far
58%
saidit'sworth it
46%
saiditworked well
19%
saidit'sa big hassle

Have you used Novolog (insulin aspart)?

Leave a review
130 reviews so far
45%
saidit'sworth it
35%
saiditworked well
22%
saidit'sa big hassle

Have you used Levemir (insulin detemir)?

Leave a review
Side effects
The Novolog (insulin aspart) FDA package insert doesn’t have numbers about how common side effects are.
5possible side effects
  • Upper respiratory tract infection
    26%
  • Headache
    23%
  • Sore throat
    10%
  • Flu-like symptoms
    8%
  • Stomach pain
    6%
See more detailed side effects
Risks and risk factors
  • Life-threatening low blood sugar (Hypoglycemia)
    • Insulin dose too high
    • Use of other blood sugar lowering medicines
    • Poor injection techniques
    • Changes in meal pattern or exercise
    • Kidney problems
    • Liver problems
  • Complications due to low potassium
    • Use of medications that lower potassium
    • Current imbalance of electrolytes
  • Severe allergic reactions
    • Allergy to insulin
See more detailed risks and warnings
  • Life-threatening low blood sugar (Hypoglycemia)
    • Insulin dose too high
    • Use of other blood sugar lowering medicines
    • Poor injection techniques
  • Complications due to low potassium
    • Use of other medicine that lower potassium
    • Current electrolyte imbalance
  • Severe allergic reactions
    • Allergy to insulin
See more detailed risks and warnings