Compare Nyquil Cold And Flu vs. Tylenol Sinus
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Relieves cold and flu symptoms, and helps you sleep.
Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine) is a useful combination medicine that relieves cold and flu symptoms and will help you sleep. Make sure you really need all of its ingredients.
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3.8/ 5 average rating with 1188 reviewsforNyquil Cold And Flu
Relieves pain and congestion.
Tylenol Sinus (Acetaminophen / Phenylephrine) is a good combination medicine to relieve pain and congestion. Be careful to not take too much acetaminophen (APAP) each day.
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3.6/ 5 average rating with 1176 reviewsforTylenol Sinus
Upsides
- Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have watery eyes, a cough, fever, and pain.
- The cough medicine (dextromethorphan) works well and has very few side effects.
- The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than other pain medications like aspirin or ibuprofen.
- The antihistamine (doxylamine) will help you sleep.
- Tylenol Sinus (Acetaminophen / Phenylephrine) is a combination medicine that relieves multiple cold symptoms. It's good to use if you have a stuffy nose, a headache, and pain.
- The decongestant (phenylephrine) has fewer side effects than other decongestants like pseudoephedrine. It doesn't raise your blood pressure and heart rate as much, or cause as much trouble falling asleep.
- The pain reliever (acetaminophen) is easier on your stomach and has fewer drug interactions than to other pain medications like aspirin or ibuprofen.
Downsides
- If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
- You shouldn't use it if you have high blood pressure.
- To avoid hurting your liver, you have to keep track of the total amount of acetaminophen (APAP) you're taking since it's a very common ingredient in pain and cold/flu combination medicines.
- If you don't really need all of the medications in this combination, you're taking extra medicine and might have extra side effects for no reason.
- Phenylephrine doesn't last as long as other decongestants like pseudoephedrine.
- You shouldn't use it if you have high blood pressure.
- To avoid hurting your liver, you need to keep track of the total amount of acetaminophen (APAP) you are taking since it is a very common ingredient in pain and cold/flu combination medicines.
Used for
Dosage forms
- Pill
- Liquid
- Pill
Price
Lowest price
$7.45
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Reviews
1188 reviews so far
83%
saidit'sworth it
42%
saiditworked well
7%
saidit'sa big hassle
Have you used Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine)?
Leave a review1176 reviews so far
74%
saidit'sworth it
31%
saiditworked well
5%
saidit'sa big hassle
Have you used Tylenol Sinus (Acetaminophen / Phenylephrine)?
Leave a reviewSide effects
The Nyquil Cold And Flu (Acetaminophen / Dextromethorphan / Doxylamine) FDA package insert doesn’t have numbers about how common side effects are.
The Tylenol Sinus (Acetaminophen / Phenylephrine) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
- Liver damage
- Drinking more than 2 alcoholic beverages a day
- Taking with other Tylenol-containing medicines
- History of liver disease
- Serotonin syndrome
- Using other medications that affect serotonin
- Driving impairment
- Taking with alcohol
- Taking with other medicines that make you less alert
- Antihistamine side effects
- Age 65 years or older
- Glaucoma
- Benign prostatic hypertrophy (BPH)
- Liver damage
- Drinking more than 2 alcoholic beverages a day
- Taking with other Tylenol-containing medicines
- History of liver disease
- High blood pressure
- History of high blood pressure
- Taking MAO inhibitors
- Harm to fetus
- Women of childbearing age