Compare olopatadine vs. Zaditor

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Pataday (olopatadine)

Prescription only

Zaditor (ketotifen)

Over-the-counter
Relieves itchy eyes due to allergies.

Pataday (olopatadine) is an effective treatment for itchy eyes due to allergies, but it doesn't treat eye irritation caused by infections or contact lens wear.

Relieves itchy eyes due to allergies.

Zaditor (ketotifen) is the first-choice OTC treatment for allergy-related itchy eyes, but it doesn't treat infections and may not help for more serious allergies.

Upsides
  • Starts working in less than 30 minutes.
  • Safe to use in children age 2 or older.
  • Pataday (olopatadine) is available in a once daily formulation.
  • Most people experience little side effects since the medicine works in your eyes and doesn't affect the rest of your body.
  • Safe to be used together with other oral medicines that also treat allergies.
  • Works within minutes to relieve itchy eyes.
  • Available to buy over-the-counter, which makes it cheaper.
  • Can use in children age 3 or older.
  • Unlike pills which can affect your whole body, Zaditor (ketotifen) only affects your eyes, which means it has less side effects than anti-allergy pills.
Downsides
  • Available as a prescription only.
  • Pataday (olopatadine) comes in a generic form, but is still relatively expensive compared to its alternatives.
  • Doesn't help relieve itch related to infections or contact lens wear.
  • Good control of hand and eye movements is needed in order to get the medicine into the eyes successfully.
  • Can only use Zaditor (ketotifen) for a short period of time.
  • Administering the medication into the eye safely may be more difficult for some people than taking anti-allergy pills.
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Used for
  • Allergy-related itchy eyes
Dosage forms
  • Eye drops
  • Eye drops
Price
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Reviews
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Side effects
The Pataday (olopatadine) FDA package insert doesn’t have numbers about how common side effects are.
The Zaditor (ketotifen) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • For external use only
  • Not to be used with contact lenses
  • Keeping the applicator clean
See more detailed risks and warnings
  • Allergy to ingredients
  • Risk for eye infection
  • Not to be used with contact lenses
    • Those who wear soft contact lenses
See more detailed risks and warnings