Compare Onglyza vs. Prandin
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Lowers blood sugar.
Onglyza (saxagliptin) can cause heart failure unlike other medicines that work just like it.
Lowers blood sugar.
Prandin (repaglinide) works quickly to lower blood sugar, especially during mealtimes. However, it can cause hypoglycemia (low blood sugar) if you are not consistent with your diet and exercise schedule.
Upsides
- DRUG-NAME is an oral blood sugar lowering medicine. It's a good option if you don't like injections.
- Does not cause weight gain.
- May be a good option for those with bad liver function.
- Does not cause hypoglycemia (low blood sugar) when taken by itself.
- Quickly and effectively lowers blood sugar during meal times.
- Less likely to cause hypoglycemia (low blood sugar) than Starlix (nateglinide).
- Good first-choice if you cannot tolerate metformin or add-on therapy if your blood sugars are not controlled on metformin alone.
Downsides
- Typically not first-choice treatment for diabetes.
- Only lowers A1C (average blood sugar over time) by ~0.5%.
- Risk for heart failure has not been seen in other medicines that work just like it.
- May be more expensive than other anti-diabetic medicines.
- May cause some weight gain.
- May cause hypoglycemia (low blood sugar).
- Can frequently interfere with how other medicines work.
- Not a good choice if you have poor kidney function, liver problems, or younger than 18 years old.
Used for
Dosage forms
- Pill
- Pill
Price
Lowest price
$464.73
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$16.81
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Reviews
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Side effects
The Onglyza (saxagliptin) FDA package insert doesn’t have numbers about how common side effects are.
20possible side effects
- Low blood sugar31%
- Headache11%
- Sinusitis6%
- Joint pain6%
- Nausea5%
- Diarrhea5%
- Back pain5%
- Swelling in arms and legs5%
- Heart failure4%
- Rhinitis3%
- Constipation3%
- Vomiting3%
- Tingling, numbness, or burning sensation on the skin3%
- Chest pain3%
- Weight gain3%
- Inflammation of the airways2%
- Indigestion2%
- Urinary tract infection2%
- Tooth disorder2%
- Allergy2%
Risks and risk factors
- inflammation of the pancreas
- Alcoholism
- Elevated triglycerides
- History of pancreatitis
- Gallstones
- Heart failure
- History of heart failure
- Bad kidney function
- Low blood sugar (hypoglycemia)
- Alcohol
- Unexpected changes in diet
- Changes in amount of exercise
- Taking other anti-diabetic medications
- Severe allergic reactions
- Severe joint pain
- Fluid-filled blisters on the skin (bullous pemphigoid)
- Low blood sugar (hypoglycemia)
- Alcoholism
- Changes in meal pattern
- Changes in exercise
- Insulin
- Other antidiabetic medications
- Elderly
- Bad liver or kidney function
- Heart damage
- use with NPH-insulin