Compare Onglyza vs. Victoza

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Onglyza (saxagliptin)

Prescription only

Victoza (liraglutide)

Prescription only
Lowers blood sugar.

Onglyza (saxagliptin) can cause heart failure unlike other medicines that work just like it.

Lowers your blood sugar.

Victoza (liraglutide) is a medicine you inject once a day to control diabetes, but it can be expensive.

4.7/ 5 average rating with 22 reviewsforVictoza
Upsides
  • DRUG-NAME is an oral blood sugar lowering medicine. It's a good option if you don't like injections.
  • Does not cause weight gain.
  • May be a good option for those with bad liver function.
  • Does not cause hypoglycemia (low blood sugar) when taken by itself.
  • Lowers A1c (average blood sugar over time) up to 1.5%.
  • Helps with weight loss and controls appetite.
  • Only medicine in this class with proven heart health benefits.
  • No limitation for people with kidney problems, but close monitoring is recommended.
  • Medicine is ready to use, without need to mix.
Downsides
  • Typically not first-choice treatment for diabetes.
  • Only lowers A1C (average blood sugar over time) by ~0.5%.
  • Risk for heart failure has not been seen in other medicines that work just like it.
  • May be more expensive than other anti-diabetic medicines.
  • Only available as an injection.
  • Brand name medicine and can be expensive.
  • Compared to other similar medicines, you have to inject this every day.
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Used for
Dosage forms
  • Pill
  • Injection
Price
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Reviews
Not enough review data.Leave a review
22 reviews so far
73%
saidit'sworth it
91%
saiditworked well
27%
saidit'sa big hassle

Have you used Victoza (liraglutide)?

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Side effects
The Onglyza (saxagliptin) FDA package insert doesn’t have numbers about how common side effects are.
2possible side effects
  • Low blood sugar - self-treatable
    27%
  • Injection site reactions
    2%
See more detailed side effects
Risks and risk factors
  • inflammation of the pancreas
    • Alcoholism
    • Elevated triglycerides
    • History of pancreatitis
    • Gallstones
  • Heart failure
    • History of heart failure
    • Bad kidney function
  • Low blood sugar (hypoglycemia)
    • Alcohol
    • Unexpected changes in diet
    • Changes in amount of exercise
    • Taking other anti-diabetic medications
  • Severe allergic reactions
  • Severe joint pain
  • Fluid-filled blisters on the skin (bullous pemphigoid)
See more detailed risks and warnings
  • Thyroid cancer
    • History of MTC
    • History of MEN 2
  • inflammation of pancreas (pancreatitis)
    • History of pancreatitis
    • History of gallstones
    • alcoholism
    • Elevated triglycerides
  • Severe allergic reactions
  • Kidney damage
    • Kidney problems
    • dehydration
  • Low blood sugar (hypoglycemia)
    • Use of insulin(s)
    • Use of insulin-secreting medicines.
  • Severe stomach problems
    • Stomach or digestive tract disease
    • Gastroparesis
See more detailed risks and warnings