Compare Onzetra vs. Relpax

Head-to-head comparisons of medication uses, side effects, ratings, and more.

ADVERTISEMENT

Onzetra (sumatriptan)

Prescription only

Relpax (eletriptan)

Prescription only
Treats migraine headaches.

Onzetra (sumatriptan) is the only medicine that's available in a breath-powered nose powder to treat migraines. However, it can be expensive compared to other medicines.

Treats migraine headaches.

Relpax (eletriptan) is a first choice medicine to treat migraines, but it can be expensive.

Upsides
  • Compared to pills, Onzetra (sumatriptan) is better absorbed in the body and good if it's hard to take pills.
  • Onzetra (sumatriptan) is a first choice medicine to treat migraines.
  • There is a copay program available that can make Onzetra (sumatriptan) cheaper.
  • Relpax (eletriptan) works as well as other first choice medicines for migraines.
  • Relpax (eletriptan) comes in 2 different strengths.
Downsides
  • It can be very expensive. There are other forms of this same medicine that are much cheaper, including a nose spray.
  • You have to use two nosepieces to get the full dose of Onzetra (sumatriptan), which can be hard to remember.
  • Onzetra (sumatriptan) is only available in one strength.
  • Relpax (eletriptan) is only available as a brand name.
  • Relpax (eletriptan) can cause dizziness and might make you more likely to fall.
  • If you have more than 3 migraines a month, Relpax (eletriptan) isn't a good choice because of its side effects.
ADVERTISEMENT
Used for
Dosage forms
  • Nasal powder
  • Pill
Price
Lowest price
$12.47
Find instant savings near you
Lowest price
$24.13
Find instant savings near you
Want to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
Not enough review data.Leave a review
Not enough review data.Leave a review
Side effects
4possible side effects
  • Changes in taste
    20%
  • Discomfort in the nose
    11%
  • Runny nose
    5%
  • Stuffy nose
    2%
See more detailed side effects
8possible side effects
  • Nausea
    4%
  • Headache
    4%
  • Weakness
    4%
  • Tingling or prickling sensation
    3%
  • Dizziness
    3%
  • Sleepiness
    3%
  • Flushing
    2%
  • Dry mouth
    2%
See more detailed side effects
Risks and risk factors
  • Heart attack
    • Heart disease
    • History of chest pain
    • Uncontrolled high blood pressure
  • Stroke
    • History of a stroke
  • Medication overuse headache
    • Using Onzetra (sumatriptan) for more than 10 days a month
  • Serotonin syndrome
    • Tricyclic antidepressants
    • Fentanyl
    • Tramadol
    • Buspirone
    • ADHD medicines
    • Triptans
  • Higher blood pressure
    • Uncontrolled high blood pressure
  • Suicidal behavior
    • Taking medicines for seizures
  • Blood vessel issues
    • High blood pressure
    • History of stroke
See more detailed risks and warnings
  • Heart attack and rhythm problems
    • Heart rhythm problems
    • History of chest pain
    • Uncontrolled high blood pressure
  • Stroke
    • History of a stroke
  • Medication overuse headache
    • Using Relpax (eletriptan) for more than 10 days a month
  • Serotonin syndrome
    • Tricyclic antidepressants
    • Fentanyl
    • Tramadol
    • Buspirone
    • ADHD medicines
    • Triptans
  • Higher blood pressure
    • Uncontrolled high blood pressure
  • Blood vessel issues
    • High blood pressure
    • History of stroke
    • History of heart attack
See more detailed risks and warnings
Learn more about Onzetra (sumatriptan)
Learn more about Relpax (eletriptan)