Compare oxybutynin vs. Vesicare

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Ditropan (oxybutynin)

Prescription or OTC

Vesicare (solifenacin)

Prescription only
Treats overactive bladder.

Ditropan (oxybutynin) is good treatment for overactive bladder, but has more side-effects like dry mouth and constipation than other medicines that work similarly.

Treats overactive bladder.

Vesicare (solifenacin) is a good choice for treatment of overactive bladder if exercises and other behavioral methods haven't worked.

Upsides
  • Available in several different formulations (pill, liquid, gel, patch) that help fit individual preferences.
  • The pill form is available in a cheap, generic version.
  • Works just as well as newer medications on the market in managing symptoms of an overactive bladder.
  • The patch form causes less side effects than the other forms of Ditropan (oxybutynin).
  • Vesicare (solifenacin) helps you to urinate less often.
  • Its once daily dosing is more convenient than other medicines that work like it.
Downsides
  • Raises the risk of falls, especially in older people.
  • Ditropan (oxybutynin) may not be a good treatment option if you also have narrow-angle glaucoma.
  • Causes more side effects like dry mouth than newer medications used for treating overactive bladder.
  • Older people who use Ditropan (oxybutynin) are at higher risk of experiencing memory problems as well as side effects such as confusion and blurry vision.
  • Can cause drowsiness and increase the risk of falls, especially in the elderly.
  • Not a good option if you have untreated, narrow-angle glaucoma.
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Used for
Dosage forms
  • Pill
  • Extended-release pill
  • Liquid
  • Patch
  • Gel
  • Pill
Price
Lowest price
$20.90
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Lowest price
$369.70
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Reviews
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Side effects
17possible side effects
  • Dry mouth
    35%
  • Constipation
    9%
  • Headache
    8%
  • Diarrhea
    8%
  • Insomnia
    6%
  • Drowsiness
    6%
  • Dizziness
    5%
  • Upset stomach
    5%
  • Nausea
    5%
  • Blurry vision
    4%
  • Dry eyes
    3%
  • Fatigue
    3%
  • Taste changes
    2%
  • Cough
    2%
  • Dry throat
    2%
  • Dry nose
    2%
  • Inability to urinate
    2%
See more detailed side effects
8possible side effects
  • Dry mouth
    11%
  • Constipation
    5%
  • Blurry vision
    4%
  • Urinary tract infection
    3%
  • Nausea
    2%
  • Upper abdominal pain
    2%
  • Flu
    2%
  • Dizziness
    2%
See more detailed side effects
Risks and risk factors
  • Drowsiness and confusion
    • Taking with alcohol
    • Taking other medicines that make you less alert
  • Vision changes
    • Glaucoma
  • Trouble urinating
    • History of bladder problems
    • History of problems with your intestine
    • Taking more than one medicine for overactive bladder or taking allergy medicines
  • More side effects
    • Taking high doses
    • Age over 65 years
  • Heat exhaustion
    • Outside in hot weather
    • Dehydrated
    • Exercising
See more detailed risks and warnings
  • Tissue swelling
  • Drowsiness
    • Taking with alcohol
    • Taking other medicines that make you less alert
    • People age 65 or older
  • Vision changes
    • Glaucoma
  • Urinary blockage
    • Bladder outflow obstruction
  • Worsening side effects
    • History of kidney problems
    • People age 65 or older
  • Temperature dysregulation
    • Outside in hot weather
    • Dehydrated
    • Exercising
    • Added people 65 and older per Beer's Criteria
    • People age 65 and older
See more detailed risks and warnings
Learn more about Ditropan (oxybutynin)
Learn more about Vesicare (solifenacin)