Compare pantoprazole vs. Dexilant
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats heartburn and excess release of stomach acid.
Protonix (pantoprazole) is usually only taken once a day for long-lasting heartburn relief, but it can increase your risk of bone fractures if you've used it for a long time.
●●●●●
3.8/ 5 average rating with 584 reviewsforpantoprazole
Treats heartburn.
Dexilant (dexlansoprazole) is an effective medicine to treat heartburn, but can be expensive since it is only available as a brand.
●●●●●
4.7/ 5 average rating with 73 reviewsforDexilant
Upsides
- Most people can take Protonix (pantoprazole) without any noticeable day-to-day side effects.
- Protonix (pantoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
- You can take it with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
- Unlike other proton pump inhibitors, it can be taken with or without food and have the same effectiveness.
- Can be used in children age 5 or older.
- Relieves heartburn symptoms better than other stomach medicines (like Pepcid, Tagamet, and Zantac).
- Lasts longer than other alternative stomach medicines.
- Convenient once daily dosing.
- Treats GERD in children 12 to 17 years of age.
- Can be swallowed whole, or contents of the pill can be emptied into applesauce for easy swallowing.
Downsides
- Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
- Needs to be taken every single day for a certain period of time to be effective.
- Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
- Only available as a prescription medicine, not over the counter.
- Can lower the magnesium level in your body so you may need to take a supplement for it.
- Similar to other proton pump inhibitors, Dexilant (dexlansoprazole) can weaken bones when taken for a long period of time.
- Can take a few days before you start to feel the full effects.
- Dexilant (dexlansoprazole) can affect how other medicines, vitamins, and minerals get absorbed in your body.
- There's no generic version available, so it can be expensive.
Used for
- GERD
- Esophagitis
- Excess stomach acid
- Zollinger-Ellison syndrome
- H.pylori infection
- Prevention of stomach rebleeding
- Stress ulcer prevention
Dosage forms
- Pill
- Packet
- Delayed-release pill
- Dissolving tablet
Price
Lowest price
$466.16
Find instant savings near youLowest price
$307.99
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
584 reviews so far
68%
saidit'sworth it
51%
saiditworked well
13%
saidit'sa big hassle
Have you used Protonix (pantoprazole)?
Leave a review73 reviews so far
93%
saidit'sworth it
92%
saiditworked well
14%
saidit'sa big hassle
Have you used Dexilant (dexlansoprazole)?
Leave a reviewSide effects
8possible side effects
- Headache12%
- Diarrhea9%
- Nausea7%
- Stomach pain6%
- Vomiting4%
- Gas4%
- Dizziness3%
- Joint pain3%
6possible side effects
- Diarrhea5%
- Abdominal pain4%
- Nausea3%
- Upper airway infection3%
- Gas3%
- Vomiting2%
Risks and risk factors
- Weakened bones
- Using multiple daily doses and/or for 1 year or longer
- People age 65 or older
- High risk of bone fractures
- Severe diarrhea
- People who are being treated in the hospital
- Kidney problem
- Lupus
- People with lupus
- Low Vitamin B-12 level
- Taking Protonix (pantoprazole) for more than 3 years
- Low magnesium level
- Diuretics (water pills)
- Digoxin
- Possible stomach cancer
- Kidney inflammation
- Severe diarrhea
- Being hospitalized
- Antibiotic use
- Bone fractures
- High dose Dexilant (dexlansoprazole)
- Long-term treatment with Dexilant (dexlansoprazole) (more than 1 year)
- Low bone mineral density
- Aged 50 years or older
- Alcohol
- Smoking
- Taking steroids or seizure medicines
- Low magnesium and vitamin B12 levels
- Taking digoxin or diuretics
- Lupus