Compare pantoprazole vs. Prevacid
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Treats heartburn and excess release of stomach acid.
Protonix (pantoprazole) is usually only taken once a day for long-lasting heartburn relief, but it can increase your risk of bone fractures if you've used it for a long time.
●●●●●
3.8/ 5 average rating with 584 reviewsforpantoprazole
Treats heartburn and stomach ulcers.
Prevacid (lansoprazole) is an effective and inexpensive acid reducer commonly used to provide heartburn relief and help heal ulcers.
●●●●●
4.0/ 5 average rating with 21 reviewsforPrevacid
Upsides
- Most people can take Protonix (pantoprazole) without any noticeable day-to-day side effects.
- Protonix (pantoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
- You can take it with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
- Unlike other proton pump inhibitors, it can be taken with or without food and have the same effectiveness.
- Can be used in children age 5 or older.
- Most people can take Prevacid (lansoprazole) without any noticeable day-to-day side effects.
- Comes in a dissolving tablet to be placed on the tongue if you cannot or do not like to swallow pills.
- Prevacid (lansoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once a day.
- You can take it in combination with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
- Prevacid (lansoprazole) is available over-the-counter and as inexpensive, generic options.
Downsides
- Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
- Needs to be taken every single day for a certain period of time to be effective.
- Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
- Only available as a prescription medicine, not over the counter.
- Can lower the magnesium level in your body so you may need to take a supplement for it.
- Doesn't start working right away like some other acid reducers (Tums, Rolaids, or Maalox).
- May not be the best choice for patients 65 years of age and older due to risk of bone fractures and C. diff infection (bacterial).
- Is used if you have frequent heartburns that occur more than 2 days per week. Speak to your doctor or pharmacist if you only have occasional heartburn.
Used for
- GERD
- Esophagitis
- Excess stomach acid
- Zollinger-Ellison syndrome
- H.pylori infection
- Prevention of stomach rebleeding
- Stress ulcer prevention
- Stomach ulcer
- Stomach ulcer prevention while taking a nonsteroidal anti-inflammatory drug (NSAID)
- Gastroesophageal reflux disease (GERD)
- Intestinal ulcer
- Stomach bacteria infection (helicobacter pylori)
- Erosive esophagitis
- Zollinger-Ellison syndrome
- Barrett's esophagus
- Stomach ulcer prevention
- Heartburn prevention
Dosage forms
- Pill
- Packet
- Extended release
- Dissolving tablet extended release
- Liquid
Price
Lowest price
$422.82
Find instant savings near youLowest price
$29.14
Find instant savings near youWant to save even more money?
Sign up now for a 30-day trial and save up to 95% at CVS, Kroger, Albertsons, and other pharmacies.
Learn more
Reviews
584 reviews so far
68%
saidit'sworth it
51%
saiditworked well
13%
saidit'sa big hassle
Have you used Protonix (pantoprazole)?
Leave a review21 reviews so far
71%
saidit'sworth it
71%
saiditworked well
19%
saidit'sa big hassle
Have you used Prevacid (lansoprazole)?
Leave a reviewSide effects
8possible side effects
- Headache12%
- Diarrhea9%
- Nausea7%
- Stomach pain6%
- Vomiting4%
- Gas4%
- Dizziness3%
- Joint pain3%
Risks and risk factors
- Weakened bones
- Using multiple daily doses and/or for 1 year or longer
- People age 65 or older
- High risk of bone fractures
- Severe diarrhea
- People who are being treated in the hospital
- Kidney problem
- Lupus
- People with lupus
- Low Vitamin B-12 level
- Taking Protonix (pantoprazole) for more than 3 years
- Low magnesium level
- Diuretics (water pills)
- Digoxin
- Stomach cancer
- Acute kidney damage
- Clostridium difficile associated diarrhea (CDAD)
- Bone fractures
- High dose Prevacid (lansoprazole)
- Long-term treatment with Prevacid (lansoprazole)
- Low bone mineral density
- Older age
- Lupus
- Low vitamin or mineral levels