Compare pantoprazole vs. Tums

Head-to-head comparisons of medication uses, side effects, ratings, and more.

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Protonix (pantoprazole)

Prescription only

Tums (Calcium carbonate)

Over-the-counter
Treats heartburn and excess release of stomach acid.

Protonix (pantoprazole) is usually only taken once a day for long-lasting heartburn relief, but it can increase your risk of bone fractures if you've used it for a long time.

3.8/ 5 average rating with 584 reviewsforpantoprazole
Relieves heartburn.

Tums (Calcium carbonate) gives quick relief for heartburn, but does not last all day. Talk to your doctor or pharmacist about other medicines if you need additional relief.

3.8/ 5 average rating with 1373 reviewsforTums
Upsides
  • Most people can take Protonix (pantoprazole) without any noticeable day-to-day side effects.
  • Protonix (pantoprazole) lasts longer than other types of antacids (like Zantac, Pepcid, or Tums), and you only need to take it once or twice a day.
  • You can take it with a quick-acting antacid (like Maalox or Tums) if you need relief right away.
  • Unlike other proton pump inhibitors, it can be taken with or without food and have the same effectiveness.
  • Can be used in children age 5 or older.
  • Tums (Calcium carbonate) is an effective, first-line medication for hearburn.
  • Tums (Calcium carbonate) starts working in seconds.
  • Has minimal side effects.
  • Available in chewable form.
  • Is inexpensive and readily available over-the-counter.
  • Coupons are available – speak to your doctor or pharmacist.
Downsides
  • Doesn't start working as fast as some other antacids like Tums, Rolaids, or Maalox.
  • Needs to be taken every single day for a certain period of time to be effective.
  • Like with other proton pump inhibitors, long-term use can cause weak or broken bones.
  • Only available as a prescription medicine, not over the counter.
  • Can lower the magnesium level in your body so you may need to take a supplement for it.
  • Because Tums (Calcium carbonate) only lasts for 1 to 2 hours, you may need additional doses.
  • May increase calcium levels too much in people with kidney or thyroid conditions.
  • May have a chalky taste.
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Used for
Dosage forms
  • Pill
  • Packet
  • Chewable tablet
  • Liquid
Price
No pricing information available
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Reviews
584 reviews so far
68%
saidit'sworth it
51%
saiditworked well
13%
saidit'sa big hassle

Have you used Protonix (pantoprazole)?

Leave a review
1373 reviews so far
82%
saidit'sworth it
43%
saiditworked well
5%
saidit'sa big hassle

Have you used Tums (Calcium carbonate)?

Leave a review
Side effects
8possible side effects
  • Headache
    12%
  • Diarrhea
    9%
  • Nausea
    7%
  • Stomach pain
    6%
  • Vomiting
    4%
  • Gas
    4%
  • Dizziness
    3%
  • Joint pain
    3%
See more detailed side effects
The Tums (Calcium carbonate) FDA package insert doesn’t have numbers about how common side effects are.
Risks and risk factors
  • Weakened bones
    • Using multiple daily doses and/or for 1 year or longer
    • People age 65 or older
    • High risk of bone fractures
  • Severe diarrhea
    • People who are being treated in the hospital
  • Kidney problem
  • Lupus
    • People with lupus
  • Low Vitamin B-12 level
    • Taking Protonix (pantoprazole) for more than 3 years
  • Low magnesium level
    • Diuretics (water pills)
    • Digoxin
See more detailed risks and warnings
No information currently available