Compare Paxil vs. Anafranil
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Improves mood and anxiety.
Paxil (paroxetine) is effective for treating depression and anxiety, but causes more unwanted side-effects than other medicines that work like it.
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3.4/ 5 average rating with 694 reviewsforPaxil
Helps control obsessive or compulsive behaviors.
Anafranil (clomipramine) effectively treats obsessive-compulsive disorder (OCD), but has potentially intolerable side effects.
Upsides
- Available in a cheaper, generic form.
- Is convenient and can take once a day.
- Anafranil (clomipramine) can help with falling sleep.
- Anafranil (clomipramine) has a lower risk of causing heart problems compared to other medications like it.
- Safe to use by children.
Downsides
- More likely to decrease your sexual appetite and delay or prevent ejaculation than other antidepressants.
- Like most antidepressants, Paxil (paroxetine) has a high risk of suicidal thoughts and behavior when used in children and adolescents.
- May not be appropriate for you if you are elderly or suffer from dementia.
- Anafranil (clomipramine) is more likely to cause side effects than other medications for OCD.
- Anafranil (clomipramine) can affect sexual performance for men.
- It is not recommended for the elderly because it can cause fainting and falls.
Used for
Dosage forms
- Pill
- Extended release pill
- Liquid
- Pill
Price
Lowest price
$26.89
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$15.90
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Reviews
694 reviews so far
52%
saidit'sworth it
39%
saiditworked well
24%
saidit'sa big hassle
Have you used Paxil (paroxetine)?
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Side effects
29possible side effects
- Abnormal ejaculation28%
- Nausea25%
- Weakness22%
- Drowsiness22%
- Difficulty sleeping21%
- Decreased sexual appetite12%
- Dizziness11%
- Sweating9%
- Dry mouth9%
- Diarrhea9%
- Tremor9%
- Female genital disorder9%
- Decreased appetite8%
- Nervousness8%
- Constipation5%
- Anxiety5%
- Yawning5%
- Painful period5%
- Impotence5%
- Indigestion4%
- Gas4%
- Muscle pain4%
- Impaired concentration4%
- Throat inflammation4%
- Abnormal vision4%
- Trauma3%
- Agitation3%
- Vomiting2%
- Muscle twitching2%
109possible side effects
- Dry mouth84%
- Sleepiness54%
- Tremor54%
- Dizziness54%
- Headache52%
- Constipation47%
- Ejaculation failure42%
- Fatigue39%
- Nausea33%
- Increased sweating28%
- Insomnia25%
- Upset stomach22%
- Loss of appetite22%
- Sex drive changes21%
- Impotence20%
- Nervousness18%
- Weight increase18%
- Abnormal vision18%
- Sore throat14%
- Urinary problems14%
- Muscle contractions13%
- Diarrhea13%
- Joint pain13%
- Abdominal pain13%
- Runny nose12%
- Menstrual cramps12%
- Increased appetite11%
- Burning/prickling skin sensation9%
- Memory problems9%
- Anxiety9%
- Sleep disorder9%
- Rash8%
- Flushing8%
- Changes in taste8%
- Twitching7%
- Vomiting7%
- Memory impairment7%
- Chest pain7%
- Allergy7%
- Weight decrease7%
- Asthma attacks7%
- Urinary retention7%
- Itching of the skin6%
- Gas6%
- Changes in blood pressure6%
- Stuffy nose6%
- Coughing6%
- Urinary tract infection6%
- Ringing in the ears6%
- Back pain6%
- Impaired concentration5%
- Depression5%
- Tooth disorder5%
- Hot flushes5%
- Increased urination5%
- Increased muscle tone4%
- Fever4%
- Palpitation4%
- Fast heartbeat4%
- Unusual milk production4%
- Menstrual disorder4%
- Pain4%
- Ear infections4%
- Changes in heartbeat4%
- Psychosomatic disorder3%
- Yawning3%
- Confusion3%
- Speech disorder3%
- Abnormal dreaming3%
- Agitation3%
- Migraine3%
- Excess tearing3%
- Social detachment2%
- Irritability2%
- Mood swings2%
- Skin irritation2%
- Acne2%
- Dry skin2%
- Gastrointestinal disorder2%
- Difficulty swallowing2%
- Local swelling2%
- Chills2%
- Nose bleed2%
- Painful urination2%
- Bladder pain2%
- Vaginal itching2%
- Increased vaginal discharge2%
- Breast enlargement2%
- Pupil dilation2%
- Thirst2%
- Muscle twitching2%
- Tingling or burning sensation2%
- Hypertonia2%
- Panic reaction2%
- Aggressive reaction2%
- Muscle weakness2%
- Abnormal skin odor2%
- Excessive burping2%
- Sores around the mouth2%
- Lack of energy2%
- Bad breath2%
- Fainting2%
- Dyspnea2%
- Laryngitis2%
- Changes in pupils2%
- Eyelid twitching2%
- Eye allergies2%
- Balance problems2%
- Anemia2%
Risks and risk factors
- Suicidal thoughts or behavior
- Age 24 years or younger
- High levels of serotonin (Serotonin Syndrome)
- Using other medications that affect serotonin levels
- Withdrawal
- Stopping Paxil (paroxetine) suddenly
- Increased bleeding risk
- Taking other blood-thinning drugs
- Sexual dysfunction
- Suicidal thoughts or behavior
- Age 24 years or younger
- Serotonin syndrome
- Antidepressants
- Lithium
- Triptans
- St. John's wort
- Fentanyl
- Tramadol
- MAO inhibitors
- Seizures
- History of seizure
- Taking other medicines that increase seizure risk
- Brain damage
- Alcoholism
- Withdrawal symptoms
- Stopping Anafranil (clomipramine) suddenly
- Low blood pressure
- Age 65 years or older
- Eye problems