Compare Paxil vs. Prozac
Head-to-head comparisons of medication uses, side effects, ratings, and more.
Improves mood and anxiety.
Paxil (paroxetine) is effective for treating depression and anxiety, but causes more unwanted side-effects than other medicines that work like it.
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3.4/ 5 average rating with 694 reviewsforPaxil
Improves mood and helps you relax.
Prozac (fluoxetine) is good for treating depression and anxiety. It's more energizing than other antidepressants, so it may not be the best choice for people who have trouble sleeping.
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3.5/ 5 average rating with 1319 reviewsforProzac
Upsides
- Available in a cheaper, generic form.
- Is convenient and can take once a day.
- Effectively treats a variety of mental health conditions such as depression, OCD, and panic disorder.
- It's more energizing than other antidepressants, so it's good for people who have low energy.
- Might be a good option for treating children with depression and/or OCD.
- Doesn't have effects on the heart unlike other antidepressants so it may be a better treatment choice for older people.
- Can cause a significant amount of weight loss which is an added benefit for those who are overweight or obese.
Downsides
- More likely to decrease your sexual appetite and delay or prevent ejaculation than other antidepressants.
- Like most antidepressants, Paxil (paroxetine) has a high risk of suicidal thoughts and behavior when used in children and adolescents.
- May not be appropriate for you if you are elderly or suffer from dementia.
- Takes at least 1 to 2 weeks to kick in and can take up to 12 weeks for maximum effect. Prozac (fluoxetine) tends to take more time to start working compared to similar alternatives.
- Can lower your sex drive.
- Can increase the risk of suicidal thoughts and/or behavior in those age 24 or younger.
- You may need to try out several different antidepressants before you find the one that works for you.
Used for
Dosage forms
- Pill
- Extended release pill
- Liquid
- Pill
- Delayed-release pill
- Liquid
Price
Lowest price
$52.40
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$559.51
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Reviews
694 reviews so far
52%
saidit'sworth it
39%
saiditworked well
24%
saidit'sa big hassle
Have you used Paxil (paroxetine)?
Leave a review1319 reviews so far
62%
saidit'sworth it
40%
saiditworked well
16%
saidit'sa big hassle
Have you used Prozac (fluoxetine)?
Leave a reviewSide effects
29possible side effects
- Abnormal ejaculation28%
- Nausea25%
- Weakness22%
- Drowsiness22%
- Difficulty sleeping21%
- Decreased sexual appetite12%
- Dizziness11%
- Sweating9%
- Dry mouth9%
- Diarrhea9%
- Tremor9%
- Female genital disorder9%
- Decreased appetite8%
- Nervousness8%
- Constipation5%
- Anxiety5%
- Yawning5%
- Painful period5%
- Impotence5%
- Indigestion4%
- Gas4%
- Muscle pain4%
- Impaired concentration4%
- Throat inflammation4%
- Abnormal vision4%
- Trauma3%
- Agitation3%
- Vomiting2%
- Muscle twitching2%
22possible side effects
- Inability to sleep33%
- Nausea28%
- Lack of energy21%
- Anxiety15%
- Sleepiness13%
- Tremor13%
- Nervousness11%
- Yawn11%
- Indigestion10%
- Sore throat10%
- Dry mouth9%
- Flu syndrome8%
- Diarrhea8%
- Loss of appetite8%
- Sweating8%
- Impotence7%
- Abnormal ejaculation7%
- Sinus infection6%
- Lower sex drive5%
- Abnormal dreams5%
- Rash4%
- Widening of blood vessels2%
Risks and risk factors
- Suicidal thoughts or behavior
- Age 24 years or younger
- High levels of serotonin (Serotonin Syndrome)
- Using other medications that affect serotonin levels
- Withdrawal
- Stopping Paxil (paroxetine) suddenly
- Increased bleeding risk
- Taking other blood-thinning drugs
- Sexual dysfunction
- Suicidal thoughts or behavior
- Age 24 or younger
- Serotonin syndrome
- Antidepressants
- Lithium
- Ultram
- Imitrex
- Remeron
- Lexapro
- Dilaudid
- St. John's Wort
- Skin rash
- Weight loss
- People with an eating disorder
- Increased bleeding risk
- Taking NSAIDS or blood-thinning drugs
- Abnormal heart rhythm
- People with heart rhythm problems or a family history of them
- Low potassium level
- Low magnesium level
- Recent heart attack
- Using other drugs that affect heart rhythm
- Overdose
- People with liver problems